| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 355 | 47 | 25 | 0.283 | 0.349 | -0.66 | SS-2B |
| Dustin Pedroia | 342 | 51 | 42 | 0.292 | 0.368 | 1.85 | 2B |
| Kevin Youkilis | 318 | 62 | 50 | 0.301 | 0.421 | 4.40 | 1B |
| Adrian Beltre | 310 | 40 | 52 | 0.349 | 0.387 | 2.48 | 3B |
| Victor Martinez | 270 | 37 | 38 | 0.289 | 0.344 | 1.62 | CR-1B |
| J.D. Drew | 269 | 41 | 36 | 0.272 | 0.361 | 1.86 | RF |
| David Ortiz | 258 | 40 | 50 | 0.253 | 0.360 | 3.48 | DH |
| Darnell McDonald | 188 | 19 | 21 | 0.269 | 0.319 | -0.15 | CF-RF-LF |
| Bill Hall | 152 | 21 | 19 | 0.237 | 0.336 | 0.68 | LF-2B |
| Jeremy Hermida | 149 | 13 | 27 | 0.217 | 0.268 | 0.75 | RF |
| Mike Cameron | 107 | 13 | 8 | 0.265 | 0.327 | -0.27 | CF |
| Jason Varitek | 102 | 17 | 16 | 0.261 | 0.324 | 1.10 | CR |
| Mike Lowell | 91 | 5 | 13 | 0.212 | 0.308 | -0.22 | 1B-DH |
| Daniel Nava | 61 | 9 | 11 | 0.291 | 0.361 | 0.69 | LF |
| Jacoby Ellsbury | 45 | 7 | 3 | 0.250 | 0.267 | 0.01 | CF |
| Josh Reddick | 26 | 2 | 3 | 0.160 | 0.192 | -0.08 | RF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 107.0 | 2.86 | 16 | 0 | X | 3.09 |
| John Lackey | 101.0 | 4.46 | 16 | 0 | X | -0.84 |
| Clay Buchholz | 92.0 | 2.45 | 15 | 0 | X | 3.54 |
| Tim Wakefield | 86.3 | 5.21 | 12 | 4 | X | -2.25 |
| Daisuke Matsuzaka | 54.0 | 4.50 | 9 | 0 | X | -0.51 |
| Josh Beckett | 45.7 | 7.29 | 8 | 0 | X | -3.40 |
| Daniel Bard | 39.7 | 2.04 | 0 | 39 | X | 1.90 |
| Manny Delcarmen | 33.3 | 3.24 | 0 | 32 | X | 0.67 |
| Jonathan Papelbon | 33.0 | 3.82 | 0 | 32 | X | 0.21 |
| Ramon S. Ramirez | 29.3 | 4.91 | 0 | 32 | X | -0.56 |
| Hideki Okajima | 26.3 | 5.81 | 0 | 33 | X | -1.05 |
| Scott Atchison | 24.3 | 4.81 | 1 | 13 | X | -0.40 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.21 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.09 |
| Felix Doubront | 5.0 | 5.40 | 1 | 0 | X | -0.15 |
| Dustin Richardson | 2.3 | 3.86 | 0 | 5 | X | 0.01 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
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