| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Kevin Youkilis | 235 | 42 | 30 | 0.350 | 0.434 | 1.91 | 1B-3B |
| Julio Lugo | 233 | 26 | 32 | 0.225 | 0.279 | 0.49 | SS |
| Manny Ramirez | 232 | 30 | 32 | 0.284 | 0.371 | 0.93 | LF-DH |
| David Ortiz | 226 | 37 | 39 | 0.328 | 0.442 | 2.54 | DH |
| Mike Lowell | 214 | 30 | 45 | 0.337 | 0.397 | 2.73 | 3B |
| Coco Crisp | 203 | 29 | 16 | 0.236 | 0.291 | -0.16 | CF |
| J.D. Drew | 188 | 29 | 18 | 0.222 | 0.340 | 0.41 | RF |
| Jason Varitek | 171 | 24 | 27 | 0.276 | 0.374 | 1.24 | CR |
| Dustin Pedroia | 147 | 19 | 13 | 0.333 | 0.408 | -0.18 | 2B |
| Alex Cora | 86 | 9 | 13 | 0.316 | 0.349 | 0.24 | 2B-SS |
| Wily Mo Pena | 74 | 10 | 7 | 0.227 | 0.311 | 0.00 | LF |
| Eric Hinske | 64 | 9 | 5 | 0.164 | 0.266 | -0.07 | 1B-LF-RF |
| Doug Mirabelli | 49 | 2 | 4 | 0.196 | 0.245 | -0.55 | CR |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Curt Schilling | 76.0 | 3.91 | 12 | 0 | X | 0.68 |
| Daisuke Matsuzaka | 72.7 | 4.83 | 11 | 0 | X | -0.91 |
| Tim Wakefield | 68.0 | 4.24 | 11 | 0 | X | 0.09 |
| Josh Beckett | 57.7 | 2.65 | 9 | 0 | X | 2.21 |
| Julian Tavarez | 48.3 | 5.40 | 9 | 0 | X | -1.25 |
| Hideki Okajima | 27.0 | 1.00 | 0 | 25 | X | 2.07 |
| Joel Pineiro | 22.3 | 5.24 | 0 | 20 | X | -0.49 |
| Jonathan Papelbon | 20.3 | 1.77 | 0 | 20 | X | 1.20 |
| Kyle Snyder | 18.7 | 1.93 | 0 | 17 | X | 1.03 |
| J.C. Romero | 18.7 | 3.37 | 0 | 22 | X | 0.40 |
| Brendan Donnelly | 17.0 | 3.71 | 0 | 23 | X | 0.23 |
| Javier Lopez | 13.0 | 3.46 | 0 | 17 | X | 0.25 |
| Mike Timlin | 8.7 | 6.23 | 0 | 9 | X | -0.39 |
| Kason Gabbard | 5.0 | 3.60 | 1 | 0 | X | 0.08 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.37 |
| Manny Delcarmen | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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