| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Kevin Youkilis | 245 | 42 | 31 | 0.346 | 0.429 | 1.77 | 1B-3B |
| Manny Ramirez | 242 | 30 | 32 | 0.286 | 0.372 | 0.69 | LF-DH |
| Julio Lugo | 240 | 26 | 32 | 0.224 | 0.283 | 0.31 | SS |
| David Ortiz | 236 | 40 | 41 | 0.333 | 0.445 | 2.83 | DH |
| Mike Lowell | 220 | 30 | 45 | 0.332 | 0.391 | 2.58 | 3B |
| Coco Crisp | 208 | 30 | 16 | 0.237 | 0.293 | -0.18 | CF |
| J.D. Drew | 191 | 29 | 18 | 0.224 | 0.340 | 0.34 | RF |
| Jason Varitek | 176 | 26 | 28 | 0.280 | 0.375 | 1.43 | CR |
| Dustin Pedroia | 157 | 20 | 16 | 0.331 | 0.401 | 0.00 | 2B |
| Alex Cora | 89 | 9 | 13 | 0.304 | 0.337 | 0.17 | 2B-SS |
| Wily Mo Pena | 83 | 12 | 9 | 0.240 | 0.313 | 0.21 | LF |
| Eric Hinske | 67 | 9 | 5 | 0.155 | 0.254 | -0.14 | 1B-LF-RF |
| Doug Mirabelli | 53 | 2 | 4 | 0.180 | 0.226 | -0.65 | CR |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Curt Schilling | 76.0 | 3.91 | 12 | 0 | X | 0.68 |
| Daisuke Matsuzaka | 72.7 | 4.83 | 11 | 0 | X | -0.91 |
| Tim Wakefield | 68.0 | 4.24 | 11 | 0 | X | 0.09 |
| Josh Beckett | 64.0 | 2.95 | 10 | 0 | X | 2.00 |
| Julian Tavarez | 54.0 | 5.33 | 10 | 0 | X | -1.31 |
| Hideki Okajima | 28.3 | 1.27 | 0 | 26 | X | 2.00 |
| Joel Pineiro | 23.3 | 5.01 | 0 | 21 | X | -0.39 |
| Jonathan Papelbon | 21.3 | 2.11 | 0 | 21 | X | 1.09 |
| Kyle Snyder | 20.0 | 2.25 | 0 | 18 | X | 0.95 |
| J.C. Romero | 20.0 | 3.15 | 0 | 23 | X | 0.53 |
| Brendan Donnelly | 18.7 | 3.37 | 0 | 25 | X | 0.40 |
| Javier Lopez | 13.0 | 3.46 | 0 | 18 | X | 0.25 |
| Mike Timlin | 8.7 | 6.23 | 0 | 9 | X | -0.39 |
| Kason Gabbard | 5.0 | 3.60 | 1 | 0 | X | 0.08 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.37 |
| Manny Delcarmen | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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