| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Kevin Youkilis | 263 | 43 | 32 | 0.338 | 0.426 | 1.56 | 1B-3B |
| Julio Lugo | 262 | 28 | 33 | 0.214 | 0.271 | 0.11 | SS |
| Manny Ramirez | 258 | 33 | 33 | 0.293 | 0.384 | 0.73 | LF-DH |
| David Ortiz | 257 | 43 | 42 | 0.330 | 0.444 | 2.75 | DH |
| Mike Lowell | 238 | 30 | 46 | 0.313 | 0.374 | 2.26 | 3B |
| Coco Crisp | 227 | 30 | 16 | 0.224 | 0.278 | -0.62 | CF |
| J.D. Drew | 206 | 33 | 25 | 0.246 | 0.354 | 1.14 | RF |
| Jason Varitek | 195 | 27 | 31 | 0.274 | 0.364 | 1.40 | CR |
| Dustin Pedroia | 171 | 22 | 16 | 0.315 | 0.392 | -0.12 | 2B |
| Alex Cora | 97 | 9 | 13 | 0.287 | 0.320 | -0.02 | 2B-SS |
| Wily Mo Pena | 90 | 12 | 10 | 0.237 | 0.322 | 0.15 | LF |
| Eric Hinske | 72 | 10 | 5 | 0.177 | 0.278 | -0.16 | 1B-LF-RF |
| Doug Mirabelli | 57 | 2 | 4 | 0.204 | 0.246 | -0.74 | CR |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Curt Schilling | 85.0 | 3.49 | 13 | 0 | X | 1.57 |
| Daisuke Matsuzaka | 79.7 | 4.63 | 12 | 0 | X | -0.64 |
| Tim Wakefield | 74.7 | 4.22 | 12 | 0 | X | 0.12 |
| Josh Beckett | 72.0 | 2.88 | 11 | 0 | X | 2.37 |
| Julian Tavarez | 60.0 | 5.25 | 11 | 0 | X | -1.35 |
| Hideki Okajima | 31.7 | 1.14 | 0 | 28 | X | 2.33 |
| Joel Pineiro | 24.3 | 4.81 | 0 | 22 | X | -0.30 |
| Jonathan Papelbon | 22.3 | 2.01 | 0 | 22 | X | 1.18 |
| Kyle Snyder | 20.0 | 2.25 | 0 | 18 | X | 0.95 |
| J.C. Romero | 20.0 | 3.15 | 0 | 23 | X | 0.53 |
| Brendan Donnelly | 19.7 | 3.20 | 0 | 26 | X | 0.50 |
| Javier Lopez | 14.0 | 3.21 | 0 | 19 | X | 0.35 |
| Mike Timlin | 8.7 | 6.23 | 0 | 9 | X | -0.39 |
| Kason Gabbard | 5.0 | 3.60 | 1 | 0 | X | 0.08 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.37 |
| Manny Delcarmen | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
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