| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Kevin Youkilis | 320 | 45 | 41 | 0.335 | 0.419 | 1.20 | 1B-3B |
| Manny Ramirez | 316 | 40 | 42 | 0.295 | 0.392 | 0.88 | LF-DH |
| David Ortiz | 309 | 49 | 48 | 0.325 | 0.440 | 2.62 | DH |
| Julio Lugo | 309 | 32 | 33 | 0.191 | 0.252 | -0.74 | SS |
| Mike Lowell | 290 | 33 | 54 | 0.294 | 0.348 | 2.04 | 3B |
| Coco Crisp | 286 | 40 | 21 | 0.259 | 0.308 | -0.59 | CF |
| J.D. Drew | 263 | 43 | 33 | 0.249 | 0.350 | 1.54 | RF |
| Jason Varitek | 243 | 30 | 33 | 0.268 | 0.362 | 0.67 | CR |
| Dustin Pedroia | 230 | 32 | 23 | 0.322 | 0.391 | 0.15 | 2B |
| Alex Cora | 120 | 12 | 14 | 0.286 | 0.325 | -0.21 | 2B-SS |
| Wily Mo Pena | 112 | 13 | 11 | 0.218 | 0.295 | -0.22 | LF |
| Eric Hinske | 82 | 12 | 8 | 0.214 | 0.317 | 0.09 | 1B-LF-RF |
| Doug Mirabelli | 71 | 2 | 5 | 0.182 | 0.239 | -1.00 | CR |
| David Murphy | 2 | 1 | 0 | 0.500 | 0.500 | 0.06 | LF-RF-CF |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Daisuke Matsuzaka | 98.7 | 4.01 | 15 | 0 | X | 0.84 |
| Curt Schilling | 94.3 | 4.20 | 15 | 0 | X | 0.39 |
| Tim Wakefield | 93.7 | 4.52 | 15 | 0 | X | -0.30 |
| Josh Beckett | 91.0 | 3.07 | 14 | 0 | X | 2.78 |
| Julian Tavarez | 78.3 | 4.60 | 14 | 0 | X | -0.40 |
| Hideki Okajima | 37.7 | 0.96 | 0 | 34 | X | 3.01 |
| Joel Pineiro | 30.0 | 4.80 | 0 | 26 | X | -0.30 |
| Jonathan Papelbon | 27.3 | 1.65 | 0 | 27 | X | 1.74 |
| Kyle Snyder | 27.0 | 2.67 | 0 | 24 | X | 1.08 |
| Brendan Donnelly | 20.7 | 3.05 | 0 | 27 | X | 0.64 |
| J.C. Romero | 20.0 | 3.15 | 0 | 23 | X | 0.57 |
| Javier Lopez | 18.7 | 3.37 | 0 | 27 | X | 0.44 |
| Mike Timlin | 17.3 | 6.23 | 0 | 17 | X | -0.75 |
| Kason Gabbard | 8.3 | 6.48 | 2 | 0 | X | -0.41 |
| Manny Delcarmen | 5.0 | 3.60 | 0 | 5 | X | 0.09 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.36 |
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