| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Manny Ramirez | 343 | 43 | 43 | 0.285 | 0.385 | 0.64 | LF-DH |
| Kevin Youkilis | 343 | 50 | 44 | 0.329 | 0.420 | 1.48 | 1B-3B |
| David Ortiz | 341 | 50 | 49 | 0.307 | 0.422 | 2.05 | DH |
| Julio Lugo | 324 | 32 | 35 | 0.191 | 0.256 | -0.89 | SS |
| Mike Lowell | 315 | 36 | 57 | 0.296 | 0.349 | 2.06 | 3B |
| Coco Crisp | 299 | 41 | 22 | 0.263 | 0.311 | -0.70 | CF |
| J.D. Drew | 287 | 46 | 34 | 0.261 | 0.373 | 1.38 | RF |
| Jason Varitek | 265 | 31 | 35 | 0.272 | 0.362 | 0.45 | CR |
| Dustin Pedroia | 259 | 34 | 25 | 0.320 | 0.398 | -0.14 | 2B |
| Alex Cora | 137 | 15 | 15 | 0.283 | 0.321 | -0.20 | 2B-SS |
| Wily Mo Pena | 122 | 13 | 12 | 0.216 | 0.287 | -0.36 | LF |
| Eric Hinske | 94 | 13 | 11 | 0.210 | 0.309 | 0.22 | 1B-LF-RF |
| Doug Mirabelli | 78 | 2 | 7 | 0.178 | 0.231 | -0.96 | CR |
| Jacoby Ellsbury | 16 | 3 | 1 | 0.286 | 0.375 | 0.03 | LF-CF |
| David Murphy | 2 | 1 | 0 | 0.500 | 0.500 | 0.06 | LF-RF-CF |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Daisuke Matsuzaka | 114.7 | 3.53 | 17 | 0 | X | 2.22 |
| Tim Wakefield | 106.7 | 4.39 | 17 | 0 | X | -0.06 |
| Josh Beckett | 96.0 | 3.38 | 15 | 0 | X | 2.21 |
| Curt Schilling | 94.3 | 4.20 | 15 | 0 | X | 0.36 |
| Julian Tavarez | 84.0 | 4.39 | 15 | 0 | X | -0.06 |
| Hideki Okajima | 41.0 | 0.88 | 0 | 38 | X | 3.33 |
| Jonathan Papelbon | 32.0 | 1.69 | 0 | 31 | X | 2.00 |
| Joel Pineiro | 30.3 | 5.04 | 0 | 27 | X | -0.48 |
| Kyle Snyder | 30.0 | 2.40 | 0 | 26 | X | 1.37 |
| Javier Lopez | 21.0 | 3.43 | 0 | 31 | X | 0.46 |
| Brendan Donnelly | 20.7 | 3.05 | 0 | 27 | X | 0.63 |
| J.C. Romero | 20.0 | 3.15 | 0 | 23 | X | 0.57 |
| Mike Timlin | 19.3 | 5.59 | 0 | 19 | X | -0.55 |
| Kason Gabbard | 14.0 | 5.79 | 3 | 0 | X | -0.46 |
| Manny Delcarmen | 8.3 | 2.16 | 0 | 8 | X | 0.43 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.36 |
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