| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Manny Ramirez | 357 | 46 | 44 | 0.285 | 0.387 | 0.75 | LF-DH |
| David Ortiz | 352 | 55 | 51 | 0.317 | 0.435 | 2.55 | DH |
| Kevin Youkilis | 344 | 50 | 44 | 0.328 | 0.419 | 1.48 | 1B-3B |
| Julio Lugo | 335 | 33 | 37 | 0.189 | 0.257 | -0.82 | SS |
| Mike Lowell | 331 | 39 | 62 | 0.301 | 0.353 | 2.53 | 3B |
| Coco Crisp | 315 | 42 | 28 | 0.269 | 0.317 | -0.33 | CF |
| J.D. Drew | 299 | 47 | 34 | 0.262 | 0.371 | 1.22 | RF |
| Jason Varitek | 278 | 33 | 36 | 0.279 | 0.367 | 0.47 | CR |
| Dustin Pedroia | 273 | 36 | 25 | 0.319 | 0.396 | -0.25 | 2B |
| Alex Cora | 143 | 15 | 15 | 0.278 | 0.315 | -0.34 | 2B-SS |
| Wily Mo Pena | 128 | 13 | 12 | 0.216 | 0.289 | -0.50 | LF |
| Eric Hinske | 104 | 13 | 11 | 0.193 | 0.308 | -0.02 | 1B-LF-RF |
| Doug Mirabelli | 81 | 3 | 9 | 0.189 | 0.259 | -0.71 | CR |
| Jacoby Ellsbury | 18 | 3 | 1 | 0.375 | 0.444 | -0.02 | LF-CF |
| Jeff Bailey | 6 | 0 | 0 | 0.000 | 0.000 | -0.15 | X |
| David Murphy | 2 | 1 | 0 | 0.500 | 0.500 | 0.06 | LF-RF-CF |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Daisuke Matsuzaka | 114.7 | 3.53 | 17 | 0 | X | 2.23 |
| Tim Wakefield | 106.7 | 4.39 | 17 | 0 | X | -0.06 |
| Josh Beckett | 102.0 | 3.44 | 16 | 0 | X | 2.20 |
| Curt Schilling | 94.3 | 4.20 | 15 | 0 | X | 0.37 |
| Julian Tavarez | 88.7 | 4.97 | 16 | 0 | X | -1.26 |
| Hideki Okajima | 43.3 | 0.83 | 0 | 39 | X | 3.57 |
| Jonathan Papelbon | 32.7 | 1.93 | 0 | 32 | X | 1.86 |
| Kyle Snyder | 32.0 | 2.81 | 0 | 28 | X | 1.16 |
| Joel Pineiro | 30.3 | 5.04 | 0 | 27 | X | -0.48 |
| Javier Lopez | 23.0 | 3.13 | 0 | 33 | X | 0.66 |
| Mike Timlin | 22.7 | 4.76 | 0 | 21 | X | -0.21 |
| Brendan Donnelly | 20.7 | 3.05 | 0 | 27 | X | 0.63 |
| Kason Gabbard | 20.3 | 4.87 | 4 | 0 | X | -0.24 |
| J.C. Romero | 20.0 | 3.15 | 0 | 23 | X | 0.57 |
| Manny Delcarmen | 10.7 | 1.69 | 0 | 10 | X | 0.67 |
| Devern Hansack | 4.7 | 7.71 | 1 | 1 | X | -0.36 |
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