| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Grady Sizemore | 462 | 78 | 52 | 0.272 | 0.385 | 2.44 | CF |
| Casey Blake | 423 | 60 | 50 | 0.272 | 0.350 | 1.28 | 3B-1B |
| Travis Hafner | 420 | 55 | 65 | 0.262 | 0.393 | 2.41 | DH-1B |
| Jhonny Peralta | 404 | 59 | 50 | 0.281 | 0.354 | 1.64 | SS |
| Victor Martinez | 395 | 52 | 77 | 0.323 | 0.385 | 3.96 | CR-1B |
| Josh Barfield | 365 | 40 | 44 | 0.256 | 0.282 | -0.04 | 2B |
| Ryan Garko | 306 | 44 | 38 | 0.320 | 0.389 | 1.18 | 1B |
| Trot Nixon | 287 | 33 | 29 | 0.245 | 0.338 | -0.46 | RF |
| Jason Michaels | 203 | 27 | 29 | 0.283 | 0.335 | 0.95 | LF-RF |
| David Dellucci | 196 | 25 | 20 | 0.233 | 0.301 | -0.03 | LF |
| Kelly Shoppach | 107 | 19 | 17 | 0.316 | 0.374 | 1.18 | CR |
| Franklin Gutierrez | 103 | 14 | 14 | 0.312 | 0.350 | 0.44 | RF |
| Mike Rouse | 75 | 4 | 4 | 0.119 | 0.200 | -0.98 | 2B-3B-SS |
| Andy Marte | 52 | 3 | 8 | 0.180 | 0.212 | -0.11 | 3B |
| Ben Francisco | 43 | 7 | 7 | 0.282 | 0.326 | 0.43 | LF |
| Shin-Soo Choo | 20 | 4 | 5 | 0.294 | 0.350 | 0.46 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| C.C. Sabathia | 146.3 | 3.81 | 21 | 0 | X | 1.84 |
| Fausto Carmona | 122.7 | 3.52 | 19 | 0 | X | 2.38 |
| Paul Byrd | 113.7 | 4.43 | 18 | 0 | X | -0.22 |
| Cliff Lee | 87.7 | 5.95 | 15 | 0 | X | -3.28 |
| Jeremy Sowers | 62.3 | 6.93 | 12 | 0 | X | -3.75 |
| Jake Westbrook | 59.3 | 6.07 | 11 | 0 | X | -2.37 |
| Rafael Betancourt | 45.0 | 1.20 | 0 | 41 | X | 3.31 |
| Tom Mastny | 39.7 | 4.54 | 0 | 37 | X | -0.17 |
| Joe Borowski | 38.7 | 5.12 | 0 | 41 | X | -0.69 |
| Fernando Cabrera | 32.7 | 5.79 | 0 | 23 | X | -1.09 |
| Rafael Perez | 30.0 | 2.10 | 0 | 18 | X | 1.58 |
| Roberto Hernandez | 26.0 | 6.23 | 0 | 28 | X | -1.14 |
| Jason Stanford | 23.0 | 4.30 | 2 | 4 | X | 0.03 |
| Aaron Fultz | 21.0 | 1.71 | 0 | 32 | X | 1.29 |
| Jason Davis | 11.3 | 4.76 | 0 | 8 | X | -0.11 |
| Edward Mujica | 7.7 | 10.57 | 0 | 5 | X | -1.11 |
| Jensen Lewis | 4.3 | 2.08 | 0 | 3 | X | 0.23 |
| Mike Koplove | 4.0 | 4.50 | 0 | 3 | X | -0.01 |
| Matt Miller | 1.0 | 0.00 | 0 | 2 | X | 0.10 |
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