| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Grady Sizemore | 632 | 102 | 70 | 0.277 | 0.386 | 2.32 | CF |
| Casey Blake | 571 | 68 | 66 | 0.267 | 0.338 | -0.15 | 3B-1B |
| Jhonny Peralta | 554 | 75 | 65 | 0.271 | 0.336 | 0.90 | SS |
| Travis Hafner | 549 | 72 | 80 | 0.254 | 0.377 | 2.29 | DH-1B |
| Victor Martinez | 545 | 71 | 95 | 0.306 | 0.374 | 3.86 | CR-1B |
| Ryan Garko | 441 | 54 | 49 | 0.299 | 0.367 | -0.17 | 1B |
| Josh Barfield | 429 | 49 | 49 | 0.244 | 0.270 | -0.39 | 2B |
| Trot Nixon | 337 | 34 | 30 | 0.255 | 0.344 | -1.67 | RF |
| Jason Michaels | 257 | 34 | 36 | 0.264 | 0.311 | 0.95 | LF-RF |
| Franklin Gutierrez | 208 | 29 | 26 | 0.279 | 0.322 | 0.60 | RF |
| David Dellucci | 196 | 25 | 20 | 0.233 | 0.301 | -0.16 | LF |
| Kelly Shoppach | 148 | 23 | 26 | 0.274 | 0.324 | 1.46 | CR |
| Kenny Lofton | 114 | 15 | 8 | 0.286 | 0.351 | -0.42 | CF |
| Mike Rouse | 76 | 4 | 4 | 0.118 | 0.197 | -1.05 | 2B-3B-SS |
| Asdrubal Cabrera | 73 | 11 | 10 | 0.303 | 0.315 | 0.39 | 2B |
| Andy Marte | 52 | 3 | 8 | 0.180 | 0.212 | -0.14 | 3B |
| Ben Francisco | 48 | 7 | 7 | 0.273 | 0.312 | 0.27 | LF |
| Chris Gomez | 25 | 0 | 3 | 0.400 | 0.400 | -0.31 | X |
| Shin-Soo Choo | 20 | 4 | 5 | 0.294 | 0.350 | 0.45 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| C.C. Sabathia | 203.0 | 3.37 | 29 | 0 | X | 4.83 |
| Fausto Carmona | 179.7 | 3.31 | 27 | 0 | X | 4.54 |
| Paul Byrd | 163.3 | 4.19 | 26 | 0 | X | 0.77 |
| Jake Westbrook | 115.0 | 4.38 | 19 | 0 | X | 0.02 |
| Cliff Lee | 91.7 | 6.38 | 16 | 0 | X | -4.26 |
| Rafael Betancourt | 65.0 | 1.52 | 0 | 56 | X | 4.35 |
| Jeremy Sowers | 62.3 | 6.93 | 12 | 0 | X | -3.70 |
| Joe Borowski | 54.7 | 5.60 | 0 | 58 | X | -1.54 |
| Rafael Perez | 49.3 | 1.64 | 0 | 34 | X | 3.16 |
| Tom Mastny | 47.0 | 4.60 | 0 | 43 | X | -0.23 |
| Fernando Cabrera | 33.7 | 5.61 | 0 | 24 | X | -0.96 |
| Aaron Fultz | 30.0 | 2.70 | 0 | 40 | X | 1.18 |
| Jason Stanford | 26.3 | 4.44 | 2 | 6 | X | -0.03 |
| Roberto Hernandez | 26.0 | 6.23 | 0 | 28 | X | -1.12 |
| Aaron Laffey | 23.3 | 5.01 | 4 | 0 | X | -0.34 |
| Jensen Lewis | 16.3 | 3.31 | 0 | 16 | X | 0.41 |
| Edward Mujica | 12.7 | 8.53 | 0 | 9 | X | -1.22 |
| Jason Davis | 11.3 | 4.76 | 0 | 8 | X | -0.10 |
| Mike Koplove | 4.0 | 4.50 | 0 | 3 | X | -0.01 |
| Matt Miller | 1.0 | 0.00 | 0 | 2 | X | 0.10 |
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