| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Grady Sizemore | 741 | 118 | 78 | 0.280 | 0.393 | 2.01 | CF |
| Casey Blake | 657 | 80 | 79 | 0.269 | 0.335 | 0.23 | 3B-1B |
| Travis Hafner | 655 | 82 | 99 | 0.262 | 0.383 | 2.59 | DH-1B |
| Jhonny Peralta | 643 | 87 | 72 | 0.270 | 0.341 | 0.58 | SS |
| Victor Martinez | 641 | 82 | 110 | 0.297 | 0.371 | 4.09 | CR-1B |
| Ryan Garko | 535 | 65 | 60 | 0.290 | 0.361 | -0.29 | 1B |
| Josh Barfield | 442 | 49 | 50 | 0.242 | 0.267 | -0.68 | 2B |
| Trot Nixon | 352 | 34 | 30 | 0.252 | 0.344 | -2.10 | RF |
| Franklin Gutierrez | 295 | 38 | 36 | 0.263 | 0.312 | 0.38 | RF |
| Jason Michaels | 289 | 41 | 39 | 0.271 | 0.322 | 1.16 | LF-RF |
| David Dellucci | 197 | 25 | 20 | 0.232 | 0.299 | -0.21 | LF |
| Kenny Lofton | 194 | 24 | 15 | 0.287 | 0.340 | -0.77 | CF |
| Asdrubal Cabrera | 179 | 27 | 22 | 0.279 | 0.335 | 0.66 | 2B |
| Kelly Shoppach | 173 | 25 | 30 | 0.253 | 0.301 | 1.44 | CR |
| Mike Rouse | 76 | 4 | 4 | 0.118 | 0.197 | -1.07 | 2B-3B-SS |
| Ben Francisco | 63 | 9 | 11 | 0.271 | 0.302 | 0.52 | LF |
| Andy Marte | 57 | 3 | 8 | 0.185 | 0.228 | -0.27 | 3B |
| Chris Gomez | 51 | 3 | 4 | 0.306 | 0.294 | -0.54 | X |
| Shin-Soo Choo | 20 | 4 | 5 | 0.294 | 0.350 | 0.44 | X |
| Luis Rivas | 8 | 2 | 4 | 0.375 | 0.375 | 0.43 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| C.C. Sabathia | 241.0 | 3.21 | 34 | 0 | X | 6.74 |
| Fausto Carmona | 215.0 | 3.06 | 32 | 0 | X | 6.79 |
| Paul Byrd | 192.3 | 4.59 | 31 | 0 | X | -0.79 |
| Jake Westbrook | 145.7 | 4.32 | 24 | 0 | X | 0.29 |
| Cliff Lee | 97.3 | 6.29 | 16 | 4 | X | -4.26 |
| Rafael Betancourt | 79.3 | 1.47 | 0 | 68 | X | 5.43 |
| Jeremy Sowers | 67.3 | 6.42 | 13 | 0 | X | -3.15 |
| Joe Borowski | 64.7 | 5.15 | 0 | 68 | X | -1.12 |
| Rafael Perez | 59.7 | 1.66 | 0 | 43 | X | 3.83 |
| Tom Mastny | 56.0 | 4.66 | 0 | 50 | X | -0.33 |
| Aaron Laffey | 44.3 | 4.87 | 8 | 0 | X | -0.48 |
| Aaron Fultz | 35.7 | 3.03 | 0 | 48 | X | 1.15 |
| Fernando Cabrera | 33.7 | 5.61 | 0 | 24 | X | -0.95 |
| Jensen Lewis | 28.7 | 2.20 | 0 | 25 | X | 1.48 |
| Jason Stanford | 26.3 | 4.44 | 2 | 6 | X | -0.02 |
| Roberto Hernandez | 26.0 | 6.23 | 0 | 28 | X | -1.10 |
| Edward Mujica | 13.0 | 8.31 | 0 | 10 | X | -1.18 |
| Jason Davis | 11.3 | 4.76 | 0 | 8 | X | -0.09 |
| Mike Koplove | 6.0 | 6.00 | 0 | 5 | X | -0.22 |
| Juan Lara | 1.3 | 13.50 | 0 | 1 | X | -0.28 |
| Matt Miller | 1.0 | 0.00 | 0 | 2 | X | 0.10 |
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