| Name | PA | R | RBI | BA | OBP | SLG | POS |
|---|---|---|---|---|---|---|---|
| Orlando Cabrera | 730 | 93 | 57 | 0.281 | 0.334 | 0.371 | SS |
| Jermaine Dye | 645 | 96 | 96 | 0.292 | 0.344 | 0.541 | RF |
| Jim Thome | 602 | 93 | 90 | 0.245 | 0.362 | 0.503 | DH |
| Nick Swisher | 588 | 86 | 69 | 0.219 | 0.332 | 0.410 | 1B-CF-LF-RF |
| A.J. Pierzynski | 570 | 66 | 60 | 0.281 | 0.312 | 0.416 | CR |
| Carlos Quentin | 569 | 96 | 100 | 0.288 | 0.394 | 0.571 | LF |
| Paul Konerko | 514 | 59 | 62 | 0.240 | 0.344 | 0.438 | 1B |
| Alexei Ramirez | 509 | 65 | 77 | 0.290 | 0.317 | 0.475 | 2B-SS-CF |
| Joe Crede | 373 | 41 | 55 | 0.248 | 0.314 | 0.460 | 3B |
| Juan Uribe | 353 | 38 | 40 | 0.247 | 0.296 | 0.386 | 3B-2B |
| Brian Anderson | 193 | 24 | 26 | 0.232 | 0.272 | 0.436 | CF |
| Ken Griffey | 150 | 16 | 18 | 0.260 | 0.347 | 0.405 | CF |
| Dewayne Wise | 143 | 20 | 18 | 0.248 | 0.293 | 0.450 | LF-CF |
| Toby Hall | 136 | 7 | 7 | 0.260 | 0.304 | 0.331 | CR |
| Pablo Ozuna | 69 | 5 | 6 | 0.281 | 0.313 | 0.328 | 3B-2B |
| Josh Fields | 35 | 3 | 2 | 0.156 | 0.229 | 0.188 | 3B |
| Jerry Owens | 17 | 1 | 1 | 0.250 | 0.250 | 0.250 | |
| Chris Getz | 7 | 2 | 1 | 0.286 | 0.286 | 0.286 | |
| Jason Bourgeois | 3 | 0 | 0 | 0.333 | 0.333 | 0.667 | |
| Paul Phillips | 2 | 0 | 0 | 0.000 | 0.000 | 0.000 |
| Name | IP | ERA | Gs | Gr | SO | WHIP |
|---|---|---|---|---|---|---|
| Mark Buehrle | 218.3 | 3.79 | 34 | 0 | 140 | 1.33 |
| Javier Vazquez | 208.0 | 4.67 | 33 | 0 | 200 | 1.32 |
| Gavin Floyd | 206.0 | 3.84 | 33 | 0 | 145 | 1.26 |
| John Danks | 195.0 | 3.32 | 33 | 0 | 159 | 1.23 |
| Jose Contreras | 121.0 | 4.54 | 20 | 0 | 70 | 1.36 |
| Matt Thornton | 67.0 | 2.67 | 0 | 74 | 77 | 0.99 |
| Octavio Dotel | 67.0 | 3.76 | 0 | 72 | 92 | 1.21 |
| Bobby Jenks | 61.3 | 2.63 | 0 | 57 | 38 | 1.10 |
| Clayton Richard | 47.3 | 6.04 | 8 | 5 | 29 | 1.55 |
| Scott Linebrink | 46.0 | 3.69 | 0 | 50 | 40 | 1.08 |
| Nick Masset | 44.3 | 4.63 | 1 | 31 | 32 | 1.70 |
| Boone Logan | 42.0 | 5.95 | 0 | 55 | 42 | 1.68 |
| D.J. Carrasco | 38.3 | 3.96 | 0 | 31 | 30 | 1.14 |
| Adam Russell | 26.0 | 5.19 | 0 | 22 | 22 | 1.54 |
| Ehren Wassermann | 19.3 | 7.78 | 0 | 24 | 9 | 2.08 |
| Mike MacDougal | 17.0 | 2.12 | 0 | 16 | 12 | 1.65 |
| Lance Broadway | 14.0 | 7.07 | 1 | 6 | 7 | 1.79 |
| Horacio Ramirez | 13.0 | 7.62 | 0 | 17 | 2 | 2.46 |
| Esteban Loaiza | 3.0 | 3.00 | 0 | 3 | 1 | 1.00 |
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