| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 223 | 27 | 24 | 0.302 | 0.336 | 0.10 | 2B |
| David Ortiz | 207 | 31 | 38 | 0.249 | 0.353 | 2.36 | DH |
| Kevin Youkilis | 202 | 31 | 34 | 0.320 | 0.386 | 2.06 | 1B-3B |
| Manny Ramirez | 197 | 28 | 28 | 0.287 | 0.371 | 1.23 | LF |
| Jacoby Ellsbury | 166 | 36 | 17 | 0.290 | 0.386 | 1.65 | CF-LF-RF |
| Julio Lugo | 154 | 13 | 12 | 0.285 | 0.351 | -1.01 | SS |
| J.D. Drew | 151 | 28 | 18 | 0.283 | 0.391 | 1.27 | RF |
| Jason Varitek | 145 | 14 | 18 | 0.295 | 0.372 | -0.06 | CR |
| Mike Lowell | 126 | 15 | 15 | 0.267 | 0.317 | 0.18 | 3B |
| Coco Crisp | 113 | 13 | 10 | 0.295 | 0.319 | -0.25 | CF |
| Sean Casey | 69 | 6 | 8 | 0.355 | 0.420 | -0.16 | 1B-DH |
| Kevin Cash | 50 | 3 | 5 | 0.341 | 0.400 | -0.34 | CR |
| Jed Lowrie | 48 | 6 | 7 | 0.310 | 0.333 | 0.23 | SS-3B |
| Alex Cora | 25 | 0 | 1 | 0.409 | 0.480 | -0.48 | SS |
| Brandon Moss | 22 | 3 | 3 | 0.286 | 0.318 | 0.11 | LF-RF |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.21 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 66.0 | 3.41 | 11 | 0 | X | 1.22 |
| Daisuke Matsuzaka | 54.3 | 2.15 | 9 | 0 | X | 2.59 |
| Josh Beckett | 54.0 | 4.67 | 8 | 0 | X | -0.59 |
| Tim Wakefield | 54.0 | 4.33 | 9 | 0 | X | -0.17 |
| Clay Buchholz | 42.3 | 5.53 | 8 | 0 | X | -1.31 |
| Jonathan Papelbon | 22.0 | 2.45 | 0 | 21 | X | 0.90 |
| David Aardsma | 21.0 | 2.14 | 0 | 19 | X | 1.01 |
| Hideki Okajima | 20.0 | 0.90 | 0 | 19 | X | 1.54 |
| Manny Delcarmen | 18.3 | 5.40 | 0 | 22 | X | -0.51 |
| Javier Lopez | 18.0 | 3.00 | 0 | 23 | X | 0.50 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.65 |
| Justin Masterson | 12.3 | 1.46 | 2 | 0 | X | 0.79 |
| Mike Timlin | 12.0 | 8.25 | 0 | 15 | X | -1.13 |
| Craig Hansen | 7.3 | 6.14 | 0 | 7 | X | -0.33 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| Bartolo Colon | 5.0 | 3.60 | 1 | 0 | X | 0.07 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.63 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
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