| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 253 | 32 | 27 | 0.283 | 0.320 | 0.15 | 2B |
| David Ortiz | 236 | 35 | 40 | 0.249 | 0.356 | 2.24 | DH |
| Manny Ramirez | 222 | 32 | 34 | 0.292 | 0.378 | 1.63 | LF |
| Kevin Youkilis | 217 | 32 | 35 | 0.306 | 0.369 | 1.85 | 1B-3B |
| Jacoby Ellsbury | 193 | 37 | 19 | 0.273 | 0.373 | 1.27 | CF-LF-RF |
| J.D. Drew | 175 | 31 | 22 | 0.282 | 0.383 | 1.38 | RF |
| Julio Lugo | 174 | 16 | 13 | 0.279 | 0.345 | -1.11 | SS |
| Jason Varitek | 160 | 14 | 19 | 0.268 | 0.350 | -0.36 | CR |
| Mike Lowell | 153 | 18 | 20 | 0.270 | 0.320 | 0.33 | 3B |
| Coco Crisp | 125 | 13 | 10 | 0.267 | 0.296 | -0.57 | CF |
| Sean Casey | 81 | 6 | 8 | 0.356 | 0.420 | -0.47 | 1B-DH |
| Kevin Cash | 59 | 4 | 5 | 0.302 | 0.356 | -0.46 | CR |
| Jed Lowrie | 48 | 6 | 7 | 0.310 | 0.333 | 0.22 | SS-3B |
| Alex Cora | 31 | 0 | 1 | 0.357 | 0.419 | -0.64 | SS |
| Brandon Moss | 22 | 3 | 3 | 0.286 | 0.318 | 0.10 | LF-RF |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.22 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 71.0 | 3.55 | 12 | 0 | X | 1.14 |
| Tim Wakefield | 67.0 | 4.70 | 11 | 0 | X | -0.73 |
| Daisuke Matsuzaka | 64.0 | 2.53 | 11 | 0 | X | 2.55 |
| Josh Beckett | 61.0 | 4.43 | 9 | 0 | X | -0.27 |
| Clay Buchholz | 42.3 | 5.53 | 8 | 0 | X | -1.28 |
| David Aardsma | 24.3 | 2.96 | 0 | 22 | X | 0.72 |
| Jonathan Papelbon | 24.0 | 2.25 | 0 | 23 | X | 1.11 |
| Hideki Okajima | 22.0 | 0.82 | 0 | 21 | X | 1.75 |
| Manny Delcarmen | 21.0 | 5.14 | 0 | 24 | X | -0.44 |
| Javier Lopez | 18.7 | 3.37 | 0 | 25 | X | 0.37 |
| Mike Timlin | 15.7 | 6.89 | 0 | 18 | X | -0.97 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.64 |
| Justin Masterson | 12.3 | 1.46 | 2 | 0 | X | 0.80 |
| Bartolo Colon | 12.0 | 2.25 | 2 | 0 | X | 0.56 |
| Craig Hansen | 10.0 | 7.20 | 0 | 9 | X | -0.69 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
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