| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 259 | 32 | 27 | 0.277 | 0.313 | 0.04 | 2B |
| David Ortiz | 242 | 36 | 41 | 0.251 | 0.355 | 2.34 | DH |
| Manny Ramirez | 228 | 33 | 34 | 0.289 | 0.373 | 1.62 | LF |
| Kevin Youkilis | 223 | 33 | 35 | 0.302 | 0.363 | 1.84 | 1B-3B |
| Jacoby Ellsbury | 200 | 38 | 19 | 0.280 | 0.375 | 1.23 | CF-LF-RF |
| Julio Lugo | 176 | 16 | 13 | 0.279 | 0.352 | -1.14 | SS |
| J.D. Drew | 175 | 31 | 22 | 0.282 | 0.383 | 1.41 | RF |
| Jason Varitek | 166 | 14 | 19 | 0.259 | 0.343 | -0.48 | CR |
| Mike Lowell | 159 | 19 | 22 | 0.281 | 0.327 | 0.53 | 3B |
| Coco Crisp | 131 | 13 | 10 | 0.256 | 0.290 | -0.70 | CF |
| Sean Casey | 81 | 6 | 8 | 0.356 | 0.420 | -0.45 | 1B-DH |
| Kevin Cash | 59 | 4 | 5 | 0.302 | 0.356 | -0.46 | CR |
| Jed Lowrie | 48 | 6 | 7 | 0.310 | 0.333 | 0.22 | SS-3B |
| Alex Cora | 34 | 0 | 1 | 0.333 | 0.412 | -0.70 | SS |
| Brandon Moss | 22 | 3 | 3 | 0.286 | 0.318 | 0.11 | LF-RF |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.21 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Jeff Bailey | 1 | 0 | 0 | 0.000 | 0.000 | -0.02 | 1B |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 71.0 | 3.55 | 12 | 0 | X | 1.09 |
| Josh Beckett | 67.0 | 4.30 | 10 | 0 | X | -0.14 |
| Tim Wakefield | 67.0 | 4.70 | 11 | 0 | X | -0.77 |
| Daisuke Matsuzaka | 64.0 | 2.53 | 11 | 0 | X | 2.50 |
| Clay Buchholz | 42.3 | 5.53 | 8 | 0 | X | -1.30 |
| Jonathan Papelbon | 25.0 | 2.16 | 0 | 24 | X | 1.19 |
| David Aardsma | 24.3 | 2.96 | 0 | 22 | X | 0.71 |
| Hideki Okajima | 24.0 | 0.75 | 0 | 22 | X | 1.94 |
| Manny Delcarmen | 22.0 | 4.91 | 0 | 25 | X | -0.36 |
| Javier Lopez | 19.0 | 3.32 | 0 | 26 | X | 0.40 |
| Mike Timlin | 16.7 | 6.48 | 0 | 19 | X | -0.88 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.65 |
| Justin Masterson | 12.3 | 1.46 | 2 | 0 | X | 0.79 |
| Bartolo Colon | 12.0 | 2.25 | 2 | 0 | X | 0.55 |
| Craig Hansen | 11.7 | 6.17 | 0 | 10 | X | -0.53 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
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