| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 406 | 60 | 41 | 0.311 | 0.350 | 0.92 | 2B |
| Manny Ramirez | 355 | 54 | 55 | 0.278 | 0.377 | 2.98 | LF |
| Kevin Youkilis | 346 | 50 | 53 | 0.311 | 0.382 | 2.56 | 1B-3B |
| Jacoby Ellsbury | 335 | 53 | 26 | 0.271 | 0.343 | 0.31 | CF-LF-RF |
| J.D. Drew | 320 | 61 | 51 | 0.299 | 0.409 | 4.13 | RF |
| Mike Lowell | 303 | 39 | 54 | 0.297 | 0.356 | 2.54 | 3B |
| Julio Lugo | 291 | 25 | 19 | 0.263 | 0.347 | -2.32 | SS |
| Jason Varitek | 273 | 18 | 27 | 0.218 | 0.300 | -1.79 | CR |
| David Ortiz | 246 | 37 | 43 | 0.252 | 0.354 | 2.53 | DH |
| Coco Crisp | 230 | 27 | 21 | 0.264 | 0.309 | -0.45 | CF |
| Sean Casey | 120 | 8 | 8 | 0.360 | 0.408 | -1.18 | 1B-DH |
| Kevin Cash | 94 | 5 | 10 | 0.238 | 0.309 | -0.67 | CR |
| Brandon Moss | 72 | 5 | 8 | 0.277 | 0.333 | -0.35 | LF-RF |
| Alex Cora | 64 | 3 | 4 | 0.263 | 0.344 | -0.79 | SS |
| Jed Lowrie | 48 | 6 | 7 | 0.310 | 0.333 | 0.22 | SS-3B |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.21 | X |
| Jeff Bailey | 6 | 1 | 0 | 0.000 | 0.500 | -0.04 | 1B |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 117.7 | 3.21 | 19 | 0 | X | 2.74 |
| Tim Wakefield | 115.3 | 3.75 | 18 | 0 | X | 1.25 |
| Josh Beckett | 107.0 | 3.70 | 16 | 0 | X | 1.28 |
| Daisuke Matsuzaka | 75.0 | 3.12 | 14 | 0 | X | 1.91 |
| Justin Masterson | 54.0 | 3.67 | 9 | 0 | X | 0.69 |
| Clay Buchholz | 42.3 | 5.53 | 8 | 0 | X | -1.30 |
| Jonathan Papelbon | 37.7 | 2.39 | 0 | 38 | X | 1.60 |
| David Aardsma | 37.3 | 2.89 | 0 | 35 | X | 1.15 |
| Hideki Okajima | 37.0 | 2.92 | 0 | 37 | X | 1.12 |
| Manny Delcarmen | 36.3 | 4.46 | 0 | 40 | X | -0.21 |
| Javier Lopez | 34.7 | 2.34 | 0 | 41 | X | 1.52 |
| Bartolo Colon | 33.0 | 4.09 | 6 | 0 | X | 0.09 |
| Craig Hansen | 24.7 | 5.84 | 0 | 25 | X | -0.94 |
| Mike Timlin | 22.7 | 6.75 | 0 | 25 | X | -1.34 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.65 |
| Chris Smith | 6.3 | 2.84 | 0 | 3 | X | 0.20 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
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