| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 434 | 67 | 47 | 0.313 | 0.353 | 1.60 | 2B |
| Manny Ramirez | 380 | 60 | 62 | 0.293 | 0.389 | 3.73 | LF |
| Kevin Youkilis | 373 | 56 | 63 | 0.314 | 0.381 | 3.59 | 1B-3B |
| Jacoby Ellsbury | 364 | 57 | 27 | 0.272 | 0.341 | 0.13 | CF-LF-RF |
| J.D. Drew | 337 | 64 | 55 | 0.302 | 0.412 | 4.45 | RF |
| Mike Lowell | 328 | 43 | 57 | 0.297 | 0.360 | 2.67 | 3B |
| Julio Lugo | 307 | 27 | 22 | 0.268 | 0.352 | -2.19 | SS |
| Jason Varitek | 288 | 20 | 28 | 0.218 | 0.299 | -1.84 | CR |
| David Ortiz | 246 | 37 | 43 | 0.252 | 0.354 | 2.52 | DH |
| Coco Crisp | 234 | 27 | 21 | 0.259 | 0.303 | -0.55 | CF |
| Sean Casey | 138 | 12 | 10 | 0.373 | 0.428 | -0.99 | 1B-DH |
| Kevin Cash | 101 | 7 | 11 | 0.242 | 0.307 | -0.52 | CR |
| Brandon Moss | 86 | 7 | 11 | 0.295 | 0.337 | -0.16 | LF-RF |
| Alex Cora | 69 | 3 | 5 | 0.283 | 0.362 | -0.81 | SS |
| Jed Lowrie | 53 | 6 | 7 | 0.277 | 0.302 | 0.10 | SS-3B |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.21 | X |
| Jeff Bailey | 8 | 1 | 0 | 0.000 | 0.375 | -0.09 | 1B |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 125.0 | 3.38 | 20 | 0 | X | 2.44 |
| Tim Wakefield | 122.3 | 3.60 | 19 | 0 | X | 1.76 |
| Josh Beckett | 112.0 | 3.94 | 17 | 0 | X | 0.74 |
| Daisuke Matsuzaka | 88.3 | 2.65 | 16 | 0 | X | 3.24 |
| Justin Masterson | 54.0 | 3.67 | 9 | 0 | X | 0.70 |
| Clay Buchholz | 47.3 | 5.70 | 9 | 0 | X | -1.64 |
| Jonathan Papelbon | 40.7 | 2.43 | 0 | 41 | X | 1.69 |
| Manny Delcarmen | 39.7 | 4.54 | 0 | 43 | X | -0.29 |
| David Aardsma | 39.0 | 2.77 | 0 | 37 | X | 1.32 |
| Hideki Okajima | 38.3 | 2.82 | 0 | 39 | X | 1.25 |
| Javier Lopez | 37.0 | 2.19 | 0 | 43 | X | 1.75 |
| Bartolo Colon | 33.0 | 4.09 | 6 | 0 | X | 0.10 |
| Craig Hansen | 26.3 | 5.47 | 0 | 27 | X | -0.77 |
| Mike Timlin | 25.7 | 6.31 | 0 | 28 | X | -1.25 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.64 |
| Chris Smith | 6.3 | 2.84 | 0 | 3 | X | 0.20 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
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