| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 579 | 96 | 62 | 0.319 | 0.359 | 2.63 | 2B |
| Kevin Youkilis | 505 | 79 | 88 | 0.320 | 0.386 | 5.36 | 1B-3B |
| Jacoby Ellsbury | 471 | 69 | 37 | 0.267 | 0.327 | -0.22 | CF-LF-RF |
| J.D. Drew | 451 | 79 | 64 | 0.280 | 0.408 | 4.14 | RF |
| Mike Lowell | 427 | 52 | 67 | 0.270 | 0.335 | 2.20 | 3B |
| Manny Ramirez | 425 | 68 | 70 | 0.299 | 0.398 | 4.25 | LF |
| Jason Varitek | 389 | 31 | 36 | 0.222 | 0.314 | -2.34 | CR |
| David Ortiz | 356 | 53 | 65 | 0.263 | 0.371 | 3.81 | DH |
| Coco Crisp | 319 | 36 | 29 | 0.259 | 0.310 | -0.86 | CF |
| Julio Lugo | 307 | 27 | 22 | 0.268 | 0.352 | -2.25 | SS |
| Sean Casey | 182 | 13 | 12 | 0.345 | 0.407 | -1.76 | 1B-DH |
| Jed Lowrie | 169 | 15 | 31 | 0.303 | 0.367 | 0.76 | SS-3B |
| Kevin Cash | 125 | 9 | 11 | 0.221 | 0.288 | -0.91 | CR |
| Alex Cora | 105 | 6 | 7 | 0.292 | 0.390 | -1.17 | SS |
| Jason Bay | 88 | 20 | 17 | 0.342 | 0.398 | 1.76 | LF |
| Brandon Moss | 86 | 7 | 11 | 0.295 | 0.337 | -0.18 | LF-RF |
| Jeff Bailey | 16 | 3 | 1 | 0.231 | 0.375 | 0.03 | 1B |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.22 | X |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 167.7 | 3.17 | 26 | 0 | X | 4.43 |
| Josh Beckett | 149.3 | 4.34 | 23 | 0 | X | -0.14 |
| Tim Wakefield | 147.0 | 3.67 | 23 | 0 | X | 2.15 |
| Daisuke Matsuzaka | 126.7 | 2.77 | 22 | 0 | X | 4.52 |
| Clay Buchholz | 76.0 | 6.75 | 15 | 1 | X | -4.35 |
| Justin Masterson | 71.0 | 3.30 | 9 | 12 | X | 1.66 |
| Jonathan Papelbon | 54.7 | 1.81 | 0 | 53 | X | 3.17 |
| Manny Delcarmen | 52.7 | 4.44 | 0 | 56 | X | -0.18 |
| Hideki Okajima | 50.7 | 2.84 | 0 | 50 | X | 1.72 |
| Javier Lopez | 47.3 | 3.04 | 0 | 55 | X | 1.39 |
| David Aardsma | 43.0 | 4.19 | 0 | 42 | X | 0.11 |
| Mike Timlin | 37.3 | 5.30 | 0 | 38 | X | -0.87 |
| Bartolo Colon | 33.0 | 4.09 | 6 | 0 | X | 0.16 |
| Craig Hansen | 30.7 | 5.58 | 0 | 32 | X | -0.91 |
| Paul Byrd | 13.3 | 5.40 | 2 | 0 | X | -0.34 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.62 |
| Chris Smith | 8.3 | 2.16 | 0 | 5 | X | 0.42 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.87 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.62 |
| Charlie Zink | 4.3 | 16.62 | 1 | 0 | X | -1.25 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.67 |
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