| Name | PA | R | RBI | BA | OBP | SLG | POS |
|---|---|---|---|---|---|---|---|
| Shin-Soo Choo | 685 | 87 | 86 | 0.300 | 0.394 | 0.489 | RF-LF-DH |
| Jhonny Peralta | 645 | 57 | 83 | 0.254 | 0.316 | 0.375 | 3B-SS |
| Asdrubal Cabrera | 581 | 81 | 68 | 0.308 | 0.361 | 0.438 | SS-2B |
| Grady Sizemore | 503 | 73 | 64 | 0.248 | 0.343 | 0.445 | CF-DH |
| Victor Martinez | 435 | 56 | 67 | 0.284 | 0.368 | 0.464 | CR-1B |
| Luis Valbuena | 398 | 52 | 31 | 0.250 | 0.298 | 0.416 | 2B-SS |
| Travis Hafner | 383 | 46 | 49 | 0.272 | 0.355 | 0.470 | DH |
| Jamey Carroll | 358 | 53 | 26 | 0.276 | 0.355 | 0.340 | 2B-3B |
| Ben Francisco | 355 | 48 | 33 | 0.250 | 0.336 | 0.422 | LF-CF-RF |
| Kelly Shoppach | 327 | 33 | 40 | 0.214 | 0.335 | 0.399 | CR |
| Mark DeRosa | 314 | 47 | 50 | 0.270 | 0.342 | 0.457 | 3B-LF |
| Ryan Garko | 273 | 29 | 39 | 0.285 | 0.362 | 0.464 | 1B-DH |
| Trevor Crowe | 202 | 22 | 17 | 0.235 | 0.278 | 0.333 | LF-CF |
| Matt LaPorta | 198 | 29 | 21 | 0.254 | 0.308 | 0.442 | LF-1B-RF |
| Andy Marte | 175 | 20 | 25 | 0.232 | 0.293 | 0.400 | 1B |
| Chris Gimenez | 130 | 12 | 7 | 0.144 | 0.256 | 0.243 | 1B-LF |
| Michael Brantley | 121 | 10 | 11 | 0.313 | 0.358 | 0.348 | CF |
| Wyatt Toregas | 60 | 1 | 6 | 0.176 | 0.267 | 0.196 | CR |
| Lou Marson | 52 | 6 | 4 | 0.250 | 0.346 | 0.386 | CR |
| David Dellucci | 45 | 3 | 1 | 0.275 | 0.333 | 0.350 | DH |
| Tony Graffanino | 24 | 1 | 0 | 0.130 | 0.167 | 0.174 | |
| Josh Barfield | 20 | 5 | 2 | 0.400 | 0.400 | 0.450 | |
| Niuman Romero | 15 | 2 | 0 | 0.143 | 0.200 | 0.143 |
| Name | IP | ERA | Gs | Gr | SO | WHIP |
|---|---|---|---|---|---|---|
| Cliff Lee | 152.0 | 3.14 | 22 | 0 | 107 | 1.30 |
| David Huff | 128.0 | 5.61 | 23 | 0 | 65 | 1.56 |
| Carl Pavano | 125.3 | 5.37 | 21 | 0 | 88 | 1.38 |
| Roberto Hernandez | 125.0 | 6.32 | 24 | 0 | 79 | 1.76 |
| Jeremy Sowers | 123.0 | 5.25 | 22 | 1 | 51 | 1.51 |
| Aaron Laffey | 121.3 | 4.44 | 19 | 6 | 59 | 1.62 |
| Tomo Ohka | 71.0 | 5.96 | 6 | 12 | 31 | 1.35 |
| Jensen Lewis | 66.0 | 4.61 | 0 | 47 | 62 | 1.37 |
| Justin Masterson | 57.0 | 4.55 | 10 | 1 | 52 | 1.59 |
| Kerry Wood | 55.0 | 4.25 | 0 | 58 | 63 | 1.38 |
| Rafael Perez | 48.0 | 7.31 | 0 | 54 | 32 | 1.90 |
| Tony Sipp | 40.0 | 2.93 | 0 | 46 | 48 | 1.30 |
| Anthony Reyes | 38.0 | 6.57 | 8 | 0 | 22 | 1.64 |
| Joe Smith | 34.0 | 3.44 | 0 | 37 | 30 | 1.26 |
| Chris Perez | 33.0 | 4.32 | 0 | 32 | 38 | 1.08 |
| Rafael Betancourt | 30.3 | 3.52 | 0 | 29 | 32 | 1.30 |
| Matt Herges | 25.0 | 3.55 | 0 | 21 | 18 | 1.18 |
| Mike Gosling | 25.0 | 5.04 | 0 | 15 | 13 | 1.64 |
| Jose Veras | 24.3 | 4.38 | 0 | 22 | 22 | 1.34 |
| Carlos Carrasco | 22.0 | 8.87 | 5 | 0 | 11 | 2.28 |
| Jess Todd | 20.3 | 7.40 | 0 | 19 | 18 | 1.84 |
| Greg Aquino | 16.0 | 4.50 | 0 | 10 | 11 | 1.75 |
| Vinnie Chulk | 12.0 | 3.75 | 0 | 8 | 4 | 1.67 |
| Luis Vizcaino | 11.3 | 5.40 | 0 | 11 | 9 | 1.71 |
| Masahide Kobayashi | 9.3 | 8.38 | 0 | 10 | 4 | 1.66 |
| Zach Jackson | 8.3 | 9.35 | 1 | 2 | 10 | 2.08 |
| Scott Lewis | 4.0 | 8.31 | 1 | 0 | 3 | 1.85 |
| Winston Abreu | 2.0 | 23.14 | 0 | 3 | 3 | 3.86 |
| Rich Rundles | 1.0 | 0.00 | 0 | 1 | 1 | 2.00 |
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