| Name | PA | R | RBI | BA | OBP | SLG | POS |
|---|---|---|---|---|---|---|---|
| Ian Kinsler | 640 | 101 | 86 | 0.253 | 0.327 | 0.488 | 2B |
| Marlon Byrd | 599 | 66 | 89 | 0.283 | 0.329 | 0.479 | CF-LF |
| Michael Young | 593 | 76 | 68 | 0.322 | 0.374 | 0.518 | 3B |
| Elvis Andrus | 541 | 72 | 40 | 0.267 | 0.329 | 0.373 | SS |
| Nelson Cruz | 515 | 75 | 76 | 0.260 | 0.332 | 0.524 | RF |
| Hank Blalock | 495 | 62 | 66 | 0.234 | 0.277 | 0.459 | 1B-DH |
| David Murphy | 494 | 61 | 57 | 0.269 | 0.338 | 0.447 | LF-DH-RF |
| Chris Davis | 419 | 48 | 59 | 0.238 | 0.284 | 0.442 | 1B-3B |
| Josh Hamilton | 365 | 43 | 54 | 0.268 | 0.315 | 0.426 | CF-RF |
| Andruw Jones | 331 | 43 | 43 | 0.214 | 0.323 | 0.459 | DH-LF |
| Jarrod Saltalamacchia | 310 | 34 | 34 | 0.233 | 0.290 | 0.371 | CR |
| Taylor Teagarden | 218 | 26 | 24 | 0.217 | 0.270 | 0.374 | CR |
| Omar Vizquel | 195 | 17 | 14 | 0.266 | 0.316 | 0.345 | SS-3B-2B |
| Julio Borbon | 179 | 30 | 20 | 0.312 | 0.376 | 0.414 | DH-LF |
| Ivan Rodriguez | 104 | 14 | 13 | 0.245 | 0.279 | 0.388 | CR |
| Esteban German | 50 | 9 | 4 | 0.304 | 0.360 | 0.391 | 3B |
| Craig Gentry | 19 | 4 | 1 | 0.118 | 0.211 | 0.176 | |
| Brandon Boggs | 18 | 0 | 0 | 0.059 | 0.111 | 0.118 | |
| Joaquin Arias | 9 | 0 | 0 | 0.000 | 0.000 | 0.000 | |
| Kevin Richardson | 6 | 2 | 0 | 0.500 | 0.500 | 0.500 | |
| Greg Golson | 1 | 0 | 0 | 0.000 | 0.000 | 0.000 |
| Name | IP | ERA | Gs | Gr | SO | WHIP |
|---|---|---|---|---|---|---|
| Kevin Millwood | 198.3 | 3.67 | 31 | 0 | 123 | 1.34 |
| Scott Feldman | 189.3 | 4.08 | 31 | 3 | 113 | 1.28 |
| Derek Holland | 138.0 | 6.12 | 21 | 12 | 107 | 1.50 |
| Tommy Hunter | 112.0 | 4.10 | 19 | 0 | 64 | 1.30 |
| Vicente Padilla | 108.0 | 4.92 | 18 | 0 | 59 | 1.50 |
| Brandon McCarthy | 97.0 | 4.62 | 17 | 0 | 65 | 1.36 |
| C.J. Wilson | 73.3 | 2.81 | 0 | 74 | 84 | 1.33 |
| Dustin Nippert | 69.3 | 3.88 | 10 | 10 | 54 | 1.33 |
| Matt Harrison | 63.0 | 6.11 | 11 | 0 | 34 | 1.64 |
| Jason Jennings | 61.0 | 4.13 | 0 | 44 | 44 | 1.56 |
| Darren O'Day | 55.3 | 1.94 | 0 | 64 | 54 | 0.95 |
| Frank Francisco | 49.0 | 3.83 | 0 | 51 | 57 | 1.11 |
| Doug Mathis | 42.3 | 3.16 | 2 | 22 | 25 | 1.15 |
| Eddie Guardado | 38.0 | 4.46 | 0 | 48 | 20 | 1.41 |
| Neftali Feliz | 31.0 | 1.74 | 0 | 20 | 39 | 0.68 |
| Jason Grilli | 26.0 | 4.78 | 0 | 30 | 27 | 1.33 |
| Kris Benson | 22.0 | 8.46 | 2 | 6 | 11 | 2.02 |
| Willie Eyre | 18.0 | 4.50 | 0 | 17 | 8 | 1.33 |
| Guillermo Moscoso | 14.0 | 3.21 | 0 | 10 | 12 | 1.50 |
| Warner Madrigal | 12.3 | 9.95 | 0 | 13 | 5 | 2.37 |
| Pedro Strop | 7.0 | 7.71 | 0 | 7 | 9 | 1.43 |
| Josh Rupe | 4.3 | 15.43 | 0 | 4 | 2 | 3.64 |
| Luis Mendoza | 1.0 | 36.00 | 0 | 1 | 0 | 3.00 |
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