| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 523 | 86 | 53 | 0.295 | 0.369 | 1.88 | 2B |
| Jacoby Ellsbury | 501 | 64 | 41 | 0.298 | 0.341 | -1.16 | CF |
| Jason Bay | 480 | 75 | 86 | 0.260 | 0.388 | 5.23 | LF |
| David Ortiz | 461 | 51 | 69 | 0.224 | 0.319 | 1.39 | DH |
| Kevin Youkilis | 427 | 72 | 66 | 0.310 | 0.424 | 4.11 | 1B-3B |
| J.D. Drew | 413 | 62 | 44 | 0.254 | 0.370 | 1.09 | RF |
| Mike Lowell | 375 | 43 | 59 | 0.298 | 0.344 | 1.59 | 3B |
| Jason Varitek | 355 | 37 | 46 | 0.223 | 0.332 | 0.08 | CR |
| Nick Green | 294 | 31 | 35 | 0.232 | 0.296 | -0.22 | SS |
| Julio Lugo | 123 | 16 | 8 | 0.284 | 0.350 | -0.47 | 2B-SS |
| Rocco Baldelli | 121 | 16 | 17 | 0.261 | 0.322 | 0.52 | RF |
| George Kottaras | 99 | 14 | 9 | 0.224 | 0.303 | 0.01 | CR |
| Jeff Bailey | 91 | 14 | 10 | 0.208 | 0.330 | 0.31 | 1B |
| Mark Kotsay | 79 | 5 | 5 | 0.257 | 0.291 | -0.87 | 1B |
| Victor Martinez | 73 | 7 | 12 | 0.323 | 0.397 | 0.22 | CR-1B |
| Jed Lowrie | 63 | 2 | 7 | 0.143 | 0.206 | -0.59 | SS |
| Josh Reddick | 33 | 2 | 2 | 0.188 | 0.212 | -0.38 | LF-RF |
| Casey Kotchman | 27 | 3 | 3 | 0.208 | 0.296 | -0.03 | 1B |
| Adam LaRoche | 19 | 2 | 3 | 0.263 | 0.263 | 0.06 | 1B |
| Jonathan Van Every | 13 | 1 | 3 | 0.364 | 0.462 | 0.10 | X |
| Alex Gonzalez | 12 | 1 | 1 | 0.167 | 0.167 | -0.08 | SS |
| Aaron Bates | 12 | 1 | 2 | 0.364 | 0.417 | 0.02 | X |
| Brian Anderson | 7 | 0 | 1 | 0.167 | 0.143 | -0.07 | CF |
| Chris Woodward | 7 | 0 | 0 | 0.000 | 0.429 | -0.17 | 3B |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.04 | X |
| Gil Velazquez | 3 | 0 | 0 | 0.000 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 162.3 | 3.38 | 24 | 0 | X | 3.58 |
| Jon Lester | 153.0 | 3.71 | 24 | 0 | X | 2.22 |
| Brad Penny | 127.7 | 5.22 | 23 | 0 | X | -2.65 |
| Tim Wakefield | 108.7 | 4.31 | 17 | 0 | X | 0.05 |
| Justin Masterson | 72.0 | 4.25 | 6 | 25 | X | 0.13 |
| Jonathan Papelbon | 52.0 | 2.08 | 0 | 51 | X | 2.73 |
| Ramon Ramirez | 52.0 | 2.25 | 0 | 52 | X | 2.52 |
| Hideki Okajima | 51.0 | 2.82 | 0 | 54 | X | 1.79 |
| Manny Delcarmen | 48.3 | 3.72 | 0 | 50 | X | 0.68 |
| Takashi Saito | 42.0 | 3.00 | 0 | 42 | X | 1.30 |
| John Smoltz | 40.0 | 8.10 | 8 | 0 | X | -3.52 |
| Daniel Bard | 36.0 | 3.50 | 0 | 33 | X | 0.70 |
| Daisuke Matsuzaka | 35.0 | 8.23 | 8 | 0 | X | -3.19 |
| Clay Buchholz | 32.3 | 4.45 | 6 | 0 | X | -0.09 |
| Junichi Tazawa | 11.7 | 5.40 | 2 | 1 | X | -0.29 |
| Javier Lopez | 11.7 | 9.26 | 0 | 14 | X | -1.34 |
| Hunter Jones | 9.0 | 8.00 | 0 | 8 | X | -0.77 |
| Billy Traber | 3.7 | 14.73 | 0 | 1 | X | -0.89 |
| Fernando Cabrera | 3.0 | 6.00 | 0 | 3 | X | -0.12 |
| Michael Bowden | 2.0 | 0.00 | 0 | 1 | X | 0.20 |
| Enrique Gonzalez | 1.7 | 10.80 | 0 | 1 | X | -0.25 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
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