| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 528 | 87 | 54 | 0.295 | 0.369 | 2.01 | 2B |
| Jacoby Ellsbury | 511 | 64 | 42 | 0.298 | 0.342 | -1.25 | CF |
| Jason Bay | 490 | 77 | 88 | 0.256 | 0.384 | 5.45 | LF |
| David Ortiz | 471 | 52 | 71 | 0.224 | 0.318 | 1.50 | DH |
| Kevin Youkilis | 437 | 74 | 66 | 0.306 | 0.421 | 4.11 | 1B-3B |
| J.D. Drew | 422 | 65 | 47 | 0.260 | 0.374 | 1.53 | RF |
| Mike Lowell | 379 | 44 | 60 | 0.297 | 0.343 | 1.74 | 3B |
| Jason Varitek | 355 | 37 | 46 | 0.223 | 0.332 | 0.11 | CR |
| Nick Green | 298 | 31 | 35 | 0.228 | 0.292 | -0.29 | SS |
| Julio Lugo | 123 | 16 | 8 | 0.284 | 0.350 | -0.46 | 2B-SS |
| Rocco Baldelli | 121 | 16 | 17 | 0.261 | 0.322 | 0.53 | RF |
| George Kottaras | 99 | 14 | 9 | 0.224 | 0.303 | 0.02 | CR |
| Jeff Bailey | 91 | 14 | 10 | 0.208 | 0.330 | 0.31 | 1B |
| Victor Martinez | 83 | 9 | 14 | 0.324 | 0.398 | 0.40 | CR-1B |
| Mark Kotsay | 79 | 5 | 5 | 0.257 | 0.291 | -0.86 | 1B |
| Jed Lowrie | 63 | 2 | 7 | 0.143 | 0.206 | -0.58 | SS |
| Josh Reddick | 33 | 2 | 2 | 0.188 | 0.212 | -0.38 | LF-RF |
| Casey Kotchman | 31 | 4 | 3 | 0.214 | 0.290 | -0.02 | 1B |
| Alex Gonzalez | 20 | 2 | 2 | 0.250 | 0.250 | -0.06 | SS |
| Adam LaRoche | 19 | 2 | 3 | 0.263 | 0.263 | 0.06 | 1B |
| Jonathan Van Every | 13 | 1 | 3 | 0.364 | 0.462 | 0.10 | X |
| Aaron Bates | 12 | 1 | 2 | 0.364 | 0.417 | 0.02 | X |
| Chris Woodward | 7 | 0 | 0 | 0.000 | 0.429 | -0.17 | 3B |
| Brian Anderson | 7 | 0 | 1 | 0.167 | 0.143 | -0.06 | CF |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.04 | X |
| Gil Velazquez | 3 | 0 | 0 | 0.000 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 162.3 | 3.38 | 24 | 0 | X | 3.54 |
| Jon Lester | 161.0 | 3.58 | 25 | 0 | X | 2.78 |
| Brad Penny | 127.7 | 5.22 | 23 | 0 | X | -2.68 |
| Tim Wakefield | 108.7 | 4.31 | 17 | 0 | X | 0.03 |
| Justin Masterson | 72.0 | 4.25 | 6 | 25 | X | 0.11 |
| Ramon Ramirez | 53.0 | 2.21 | 0 | 53 | X | 2.61 |
| Jonathan Papelbon | 52.0 | 2.08 | 0 | 51 | X | 2.72 |
| Hideki Okajima | 52.0 | 2.77 | 0 | 55 | X | 1.88 |
| Manny Delcarmen | 48.3 | 3.72 | 0 | 50 | X | 0.67 |
| Takashi Saito | 43.0 | 2.93 | 0 | 43 | X | 1.39 |
| John Smoltz | 40.0 | 8.10 | 8 | 0 | X | -3.53 |
| Clay Buchholz | 38.3 | 3.99 | 7 | 0 | X | 0.29 |
| Daniel Bard | 36.0 | 3.50 | 0 | 33 | X | 0.69 |
| Daisuke Matsuzaka | 35.0 | 8.23 | 8 | 0 | X | -3.19 |
| Javier Lopez | 11.7 | 9.26 | 0 | 14 | X | -1.34 |
| Junichi Tazawa | 11.7 | 5.40 | 2 | 1 | X | -0.29 |
| Hunter Jones | 9.0 | 8.00 | 0 | 8 | X | -0.77 |
| Fernando Cabrera | 4.0 | 4.50 | 0 | 4 | X | -0.02 |
| Billy Traber | 3.7 | 14.73 | 0 | 1 | X | -0.89 |
| Michael Bowden | 2.0 | 0.00 | 0 | 1 | X | 0.20 |
| Enrique Gonzalez | 1.7 | 10.80 | 0 | 1 | X | -0.25 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
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