| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 660 | 105 | 67 | 0.297 | 0.367 | 2.15 | 2B |
| Jacoby Ellsbury | 643 | 84 | 58 | 0.302 | 0.350 | -0.59 | CF |
| Jason Bay | 595 | 98 | 115 | 0.269 | 0.388 | 8.02 | LF |
| David Ortiz | 577 | 74 | 85 | 0.232 | 0.326 | 2.78 | DH |
| Kevin Youkilis | 544 | 94 | 86 | 0.308 | 0.415 | 5.78 | 1B-3B |
| J.D. Drew | 512 | 81 | 62 | 0.266 | 0.383 | 2.67 | RF |
| Mike Lowell | 459 | 54 | 74 | 0.293 | 0.338 | 2.37 | 3B |
| Jason Varitek | 409 | 41 | 52 | 0.211 | 0.315 | -0.10 | CR |
| Nick Green | 309 | 34 | 36 | 0.236 | 0.301 | -0.10 | SS |
| Victor Martinez | 192 | 24 | 33 | 0.335 | 0.406 | 1.36 | CR-1B |
| Rocco Baldelli | 154 | 23 | 23 | 0.262 | 0.318 | 1.12 | RF |
| Julio Lugo | 123 | 16 | 8 | 0.284 | 0.350 | -0.45 | 2B-SS |
| Alex Gonzalez | 121 | 20 | 15 | 0.296 | 0.306 | 0.76 | SS |
| George Kottaras | 102 | 14 | 10 | 0.227 | 0.304 | 0.06 | CR |
| Jeff Bailey | 91 | 14 | 10 | 0.208 | 0.330 | 0.33 | 1B |
| Mark Kotsay | 79 | 5 | 5 | 0.257 | 0.291 | -0.85 | 1B |
| Casey Kotchman | 67 | 6 | 7 | 0.226 | 0.284 | -0.25 | 1B |
| Jed Lowrie | 64 | 2 | 7 | 0.158 | 0.219 | -0.60 | SS |
| Josh Reddick | 47 | 5 | 4 | 0.227 | 0.277 | -0.19 | LF-RF |
| Adam LaRoche | 19 | 2 | 3 | 0.263 | 0.263 | 0.07 | 1B |
| Jonathan Van Every | 13 | 1 | 3 | 0.364 | 0.462 | 0.11 | X |
| Aaron Bates | 12 | 1 | 2 | 0.364 | 0.417 | 0.03 | X |
| Brian Anderson | 10 | 1 | 2 | 0.222 | 0.200 | 0.07 | CF |
| Chris Woodward | 10 | 0 | 0 | 0.000 | 0.300 | -0.24 | 3B |
| Chris Carter | 6 | 0 | 1 | 0.000 | 0.000 | -0.04 | X |
| Joey Gathright | 4 | 1 | 0 | 0.500 | 0.500 | 0.01 | CF |
| Gil Velazquez | 3 | 0 | 0 | 0.000 | 0.333 | -0.07 | X |
| Dusty Brown | 1 | 0 | 0 | 0.000 | 0.000 | -0.02 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 201.3 | 3.80 | 30 | 0 | X | 2.41 |
| Jon Lester | 194.7 | 3.33 | 30 | 0 | X | 4.47 |
| Brad Penny | 131.7 | 5.61 | 24 | 0 | X | -3.97 |
| Tim Wakefield | 126.7 | 4.33 | 20 | 0 | X | -0.06 |
| Clay Buchholz | 77.3 | 3.49 | 13 | 0 | X | 1.48 |
| Justin Masterson | 72.0 | 4.25 | 6 | 25 | X | 0.11 |
| Jonathan Papelbon | 64.0 | 1.97 | 0 | 62 | X | 3.50 |
| Ramon Ramirez | 64.0 | 2.67 | 0 | 64 | X | 2.45 |
| Hideki Okajima | 59.0 | 3.36 | 0 | 66 | X | 1.32 |
| Manny Delcarmen | 56.0 | 4.66 | 0 | 60 | X | -0.45 |
| Takashi Saito | 51.7 | 2.44 | 0 | 52 | X | 2.26 |
| Daisuke Matsuzaka | 46.3 | 6.80 | 10 | 0 | X | -2.69 |
| Daniel Bard | 46.0 | 3.72 | 0 | 44 | X | 0.64 |
| John Smoltz | 40.0 | 8.10 | 8 | 0 | X | -3.53 |
| Junichi Tazawa | 25.3 | 7.46 | 4 | 2 | X | -1.86 |
| Paul Byrd | 18.7 | 5.79 | 4 | 0 | X | -0.64 |
| Javier Lopez | 11.7 | 9.26 | 0 | 14 | X | -1.35 |
| Billy Wagner | 9.3 | 2.89 | 0 | 10 | X | 0.31 |
| Hunter Jones | 9.0 | 8.00 | 0 | 8 | X | -0.77 |
| Michael Bowden | 7.0 | 9.00 | 0 | 4 | X | -0.77 |
| Fernando Cabrera | 4.0 | 4.50 | 0 | 4 | X | -0.02 |
| Billy Traber | 3.7 | 14.73 | 0 | 1 | X | -0.89 |
| Enrique Gonzalez | 3.7 | 4.91 | 0 | 2 | X | -0.05 |
| Nick Green | 2.0 | 0.00 | 0 | 1 | X | 0.20 |
| Jonathan Van Every | 0.7 | 0.00 | 0 | 1 | X | 0.07 |
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