| Name | PA | R | RBI | BA | OBP | SLG | POS |
|---|---|---|---|---|---|---|---|
| Shin-Soo Choo | 646 | 81 | 90 | 0.300 | 0.401 | 0.484 | RF |
| Trevor Crowe | 479 | 48 | 36 | 0.251 | 0.302 | 0.333 | CF-LF |
| Travis Hafner | 462 | 46 | 50 | 0.278 | 0.374 | 0.449 | DH |
| Asdrubal Cabrera | 425 | 39 | 29 | 0.276 | 0.326 | 0.346 | SS |
| Matt LaPorta | 425 | 41 | 41 | 0.221 | 0.306 | 0.362 | 1B |
| Jhonny Peralta | 373 | 37 | 43 | 0.246 | 0.308 | 0.389 | 3B |
| Austin Kearns | 342 | 42 | 42 | 0.272 | 0.354 | 0.419 | LF-RF |
| Michael Brantley | 325 | 38 | 22 | 0.246 | 0.296 | 0.327 | CF |
| Jason Donald | 325 | 39 | 24 | 0.253 | 0.312 | 0.378 | SS-2B |
| Luis Valbuena | 310 | 22 | 24 | 0.193 | 0.273 | 0.258 | 2B |
| Jayson Nix | 306 | 29 | 29 | 0.234 | 0.283 | 0.422 | 3B-2B |
| Lou Marson | 294 | 29 | 22 | 0.195 | 0.274 | 0.286 | CR |
| Shelley Duncan | 259 | 29 | 36 | 0.231 | 0.317 | 0.419 | LF-DH |
| Carlos Santana | 192 | 23 | 22 | 0.260 | 0.401 | 0.467 | CR |
| Russell Branyan | 190 | 24 | 24 | 0.263 | 0.328 | 0.491 | 1B |
| Andy Marte | 188 | 18 | 19 | 0.229 | 0.298 | 0.382 | 3B-1B |
| Grady Sizemore | 140 | 15 | 13 | 0.211 | 0.271 | 0.289 | CF |
| Mark Grudzielanek | 119 | 10 | 11 | 0.273 | 0.328 | 0.273 | 2B |
| Jordan Brown | 92 | 9 | 2 | 0.230 | 0.272 | 0.310 | 1B |
| Mike Redmond | 68 | 7 | 5 | 0.206 | 0.242 | 0.270 | CR |
| Chris Gimenez | 67 | 6 | 8 | 0.190 | 0.288 | 0.328 | CR |
| Anderson Hernandez | 63 | 6 | 2 | 0.246 | 0.270 | 0.295 | SS |
| Drew Sutton | 39 | 4 | 4 | 0.222 | 0.282 | 0.333 | |
| Luke Carlin | 16 | 4 | 3 | 0.357 | 0.438 | 0.786 |
| Name | IP | ERA | Gs | Gr | SO | WHIP |
|---|---|---|---|---|---|---|
| Roberto Hernandez | 210.0 | 3.77 | 33 | 0 | 124 | 1.31 |
| Justin Masterson | 180.0 | 4.70 | 29 | 5 | 140 | 1.50 |
| Mitch Talbot | 159.0 | 4.41 | 28 | 0 | 88 | 1.49 |
| Jake Westbrook | 127.3 | 4.65 | 21 | 0 | 73 | 1.39 |
| David Huff | 79.3 | 6.21 | 15 | 0 | 37 | 1.70 |
| Josh Tomlin | 73.0 | 4.56 | 12 | 0 | 43 | 1.25 |
| Chris Perez | 63.0 | 1.71 | 0 | 63 | 61 | 1.08 |
| Tony Sipp | 63.0 | 4.14 | 0 | 70 | 69 | 1.38 |
| Rafael Perez | 61.0 | 3.25 | 0 | 70 | 36 | 1.59 |
| Jeanmar Gomez | 57.3 | 4.68 | 11 | 0 | 34 | 1.65 |
| Aaron Laffey | 55.3 | 4.53 | 5 | 24 | 28 | 1.62 |
| Hector Ambriz | 48.0 | 5.59 | 0 | 34 | 37 | 1.76 |
| Carlos Carrasco | 44.3 | 3.83 | 7 | 0 | 38 | 1.37 |
| Frank Herrmann | 44.3 | 4.03 | 0 | 40 | 24 | 1.28 |
| Joe Smith | 40.0 | 3.83 | 0 | 53 | 32 | 1.35 |
| Jensen Lewis | 36.0 | 2.97 | 0 | 37 | 29 | 1.29 |
| Justin Germano | 35.0 | 3.31 | 1 | 22 | 29 | 0.99 |
| Jamey Wright | 21.0 | 5.48 | 0 | 18 | 9 | 1.59 |
| Kerry Wood | 20.0 | 6.30 | 0 | 23 | 18 | 1.60 |
| Jess Todd | 6.0 | 7.50 | 0 | 5 | 9 | 2.00 |
| Vinnie Pestano | 5.0 | 3.60 | 0 | 5 | 8 | 1.80 |
| Andy Marte | 1.0 | 0.00 | 0 | 1 | 1 | 0.00 |
_