| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 222 | 32 | 25 | 0.271 | 0.347 | 0.84 | 2B |
| Marco Scutaro | 213 | 28 | 8 | 0.250 | 0.338 | -1.16 | SS-2B |
| Kevin Youkilis | 208 | 42 | 29 | 0.311 | 0.457 | 2.63 | 1B |
| Adrian Beltre | 188 | 20 | 33 | 0.341 | 0.372 | 1.20 | 3B |
| J.D. Drew | 187 | 31 | 29 | 0.272 | 0.353 | 1.96 | RF |
| Victor Martinez | 171 | 22 | 20 | 0.258 | 0.310 | 0.44 | CR-1B |
| David Ortiz | 139 | 19 | 27 | 0.266 | 0.338 | 1.61 | DH |
| Jeremy Hermida | 123 | 11 | 25 | 0.230 | 0.285 | 0.93 | RF |
| Darnell McDonald | 110 | 9 | 13 | 0.270 | 0.318 | -0.24 | CF-RF-LF |
| Bill Hall | 79 | 7 | 8 | 0.188 | 0.278 | -0.26 | LF-2B |
| Mike Lowell | 72 | 4 | 9 | 0.238 | 0.333 | -0.31 | 1B-DH |
| Jason Varitek | 62 | 11 | 10 | 0.273 | 0.355 | 0.77 | CR |
| Jacoby Ellsbury | 45 | 7 | 3 | 0.250 | 0.267 | 0.01 | CF |
| Mike Cameron | 44 | 3 | 0 | 0.237 | 0.341 | -0.71 | CF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Josh Reddick | 6 | 0 | 3 | 0.167 | 0.167 | 0.18 | RF |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 65.7 | 3.15 | 10 | 0 | X | 1.42 |
| John Lackey | 61.3 | 4.84 | 10 | 0 | X | -1.10 |
| Clay Buchholz | 55.7 | 3.07 | 9 | 0 | X | 1.30 |
| Tim Wakefield | 48.7 | 4.44 | 6 | 4 | X | -0.41 |
| Josh Beckett | 45.7 | 7.29 | 8 | 0 | X | -3.43 |
| Daisuke Matsuzaka | 29.7 | 5.76 | 5 | 0 | X | -1.17 |
| Daniel Bard | 25.0 | 2.16 | 0 | 24 | X | 1.12 |
| Manny Delcarmen | 22.0 | 2.05 | 0 | 19 | X | 1.04 |
| Jonathan Papelbon | 21.0 | 3.00 | 0 | 19 | X | 0.53 |
| Ramon S. Ramirez | 18.0 | 6.00 | 0 | 18 | X | -0.81 |
| Hideki Okajima | 16.3 | 4.41 | 0 | 21 | X | -0.13 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.22 |
| Scott Atchison | 10.3 | 6.10 | 0 | 7 | X | -0.49 |
| Joe Nelson | 3.0 | 6.00 | 0 | 2 | X | -0.13 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
_