| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 298 | 37 | 32 | 0.263 | 0.339 | 0.35 | 2B |
| Marco Scutaro | 298 | 42 | 19 | 0.282 | 0.352 | -0.49 | SS-2B |
| Kevin Youkilis | 269 | 54 | 40 | 0.316 | 0.450 | 3.65 | 1B |
| Adrian Beltre | 258 | 28 | 44 | 0.335 | 0.368 | 1.59 | 3B |
| J.D. Drew | 246 | 39 | 34 | 0.274 | 0.362 | 1.97 | RF |
| Victor Martinez | 229 | 32 | 34 | 0.301 | 0.354 | 1.63 | CR-1B |
| David Ortiz | 212 | 30 | 39 | 0.251 | 0.344 | 2.34 | DH |
| Darnell McDonald | 152 | 15 | 16 | 0.281 | 0.329 | -0.26 | CF-RF-LF |
| Jeremy Hermida | 149 | 13 | 27 | 0.217 | 0.268 | 0.75 | RF |
| Bill Hall | 126 | 18 | 16 | 0.239 | 0.333 | 0.65 | LF-2B |
| Mike Lowell | 90 | 5 | 13 | 0.215 | 0.311 | -0.19 | 1B-DH |
| Jason Varitek | 85 | 16 | 12 | 0.263 | 0.341 | 0.97 | CR |
| Mike Cameron | 72 | 8 | 2 | 0.270 | 0.361 | -0.62 | CF |
| Jacoby Ellsbury | 45 | 7 | 3 | 0.250 | 0.267 | 0.01 | CF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Josh Reddick | 17 | 2 | 3 | 0.176 | 0.176 | 0.13 | RF |
| Daniel Nava | 8 | 1 | 5 | 0.500 | 0.500 | 0.44 | LF |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 85.0 | 3.18 | 13 | 0 | X | 1.82 |
| John Lackey | 81.3 | 4.54 | 13 | 0 | X | -0.84 |
| Clay Buchholz | 78.7 | 2.52 | 12 | 0 | X | 2.90 |
| Tim Wakefield | 73.0 | 5.42 | 10 | 4 | X | -2.26 |
| Daisuke Matsuzaka | 49.0 | 4.59 | 8 | 0 | X | -0.57 |
| Josh Beckett | 45.7 | 7.29 | 8 | 0 | X | -3.41 |
| Daniel Bard | 32.7 | 2.48 | 0 | 31 | X | 1.23 |
| Manny Delcarmen | 30.0 | 2.40 | 0 | 26 | X | 1.19 |
| Ramon S. Ramirez | 25.7 | 5.26 | 0 | 27 | X | -0.70 |
| Jonathan Papelbon | 25.0 | 2.88 | 0 | 23 | X | 0.71 |
| Hideki Okajima | 20.3 | 4.87 | 0 | 26 | X | -0.37 |
| Scott Atchison | 17.0 | 4.76 | 1 | 9 | X | -0.27 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.21 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.09 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
| Dustin Richardson | 0.7 | 0.00 | 0 | 1 | X | 0.06 |
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