| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Marco Scutaro | 345 | 46 | 24 | 0.282 | 0.348 | -0.63 | SS-2B |
| Dustin Pedroia | 342 | 51 | 42 | 0.292 | 0.368 | 1.85 | 2B |
| Kevin Youkilis | 308 | 60 | 50 | 0.304 | 0.425 | 4.42 | 1B |
| Adrian Beltre | 305 | 37 | 51 | 0.338 | 0.377 | 2.18 | 3B |
| Victor Martinez | 268 | 36 | 38 | 0.290 | 0.343 | 1.57 | CR-1B |
| J.D. Drew | 261 | 40 | 36 | 0.273 | 0.356 | 1.94 | RF |
| David Ortiz | 249 | 38 | 46 | 0.252 | 0.357 | 3.06 | DH |
| Darnell McDonald | 183 | 19 | 21 | 0.270 | 0.317 | -0.03 | CF-RF-LF |
| Jeremy Hermida | 149 | 13 | 27 | 0.217 | 0.268 | 0.75 | RF |
| Bill Hall | 144 | 19 | 16 | 0.226 | 0.326 | 0.34 | LF-2B |
| Mike Cameron | 103 | 12 | 8 | 0.266 | 0.330 | -0.28 | CF |
| Jason Varitek | 95 | 17 | 14 | 0.267 | 0.337 | 1.06 | CR |
| Mike Lowell | 91 | 5 | 13 | 0.212 | 0.308 | -0.22 | 1B-DH |
| Daniel Nava | 52 | 9 | 10 | 0.304 | 0.385 | 0.79 | LF |
| Jacoby Ellsbury | 45 | 7 | 3 | 0.250 | 0.267 | 0.01 | CF |
| Josh Reddick | 26 | 2 | 3 | 0.160 | 0.192 | -0.08 | RF |
| Jonathan Van Every | 21 | 5 | 1 | 0.211 | 0.286 | 0.14 | CF |
| Angel Sanchez | 3 | 0 | 0 | 0.000 | 0.000 | -0.07 | SS |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 98.0 | 3.03 | 15 | 0 | X | 2.43 |
| John Lackey | 94.0 | 4.69 | 15 | 0 | X | -1.31 |
| Clay Buchholz | 92.0 | 2.45 | 15 | 0 | X | 3.54 |
| Tim Wakefield | 86.3 | 5.21 | 12 | 4 | X | -2.26 |
| Daisuke Matsuzaka | 54.0 | 4.50 | 9 | 0 | X | -0.51 |
| Josh Beckett | 45.7 | 7.29 | 8 | 0 | X | -3.41 |
| Daniel Bard | 39.3 | 2.06 | 0 | 38 | X | 1.87 |
| Manny Delcarmen | 33.3 | 3.24 | 0 | 32 | X | 0.66 |
| Jonathan Papelbon | 32.7 | 3.86 | 0 | 31 | X | 0.18 |
| Ramon S. Ramirez | 29.3 | 4.91 | 0 | 32 | X | -0.56 |
| Hideki Okajima | 25.7 | 5.26 | 0 | 32 | X | -0.70 |
| Scott Atchison | 24.0 | 4.12 | 1 | 12 | X | -0.02 |
| Scott Schoeneweis | 13.7 | 7.90 | 0 | 15 | X | -1.21 |
| Joe Nelson | 8.3 | 9.72 | 0 | 8 | X | -1.09 |
| Felix Doubront | 5.0 | 5.40 | 1 | 0 | X | -0.15 |
| Dustin Richardson | 2.0 | 4.50 | 0 | 4 | X | -0.02 |
| Boof Bonser | 2.0 | 18.00 | 0 | 2 | X | -0.65 |
| Bill Hall | 1.0 | 0.00 | 0 | 1 | X | 0.10 |
| Jonathan Van Every | 1.0 | 18.00 | 0 | 1 | X | -0.32 |
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