| Name | PA | R | RBI | BA | OBP | SLG | POS |
|---|---|---|---|---|---|---|---|
| Jacoby Ellsbury | 732 | 119 | 105 | 0.321 | 0.376 | 0.552 | CF |
| Dustin Pedroia | 731 | 102 | 91 | 0.307 | 0.387 | 0.474 | 2B |
| Adrian Gonzalez | 715 | 108 | 117 | 0.338 | 0.410 | 0.548 | 1B |
| David Ortiz | 605 | 84 | 96 | 0.309 | 0.398 | 0.554 | DH |
| Carl Crawford | 539 | 65 | 56 | 0.255 | 0.289 | 0.405 | LF |
| Kevin Youkilis | 517 | 68 | 80 | 0.258 | 0.373 | 0.459 | 3B |
| Marco Scutaro | 445 | 59 | 54 | 0.299 | 0.358 | 0.423 | SS |
| Jarrod Saltalamacchia | 386 | 52 | 56 | 0.235 | 0.288 | 0.450 | CR |
| Jed Lowrie | 341 | 40 | 36 | 0.252 | 0.303 | 0.382 | SS-3B |
| J.D. Drew | 286 | 23 | 22 | 0.222 | 0.315 | 0.302 | RF |
| Josh Reddick | 278 | 41 | 28 | 0.280 | 0.327 | 0.457 | RF-LF |
| Jason Varitek | 250 | 32 | 36 | 0.221 | 0.300 | 0.423 | CR |
| Darnell McDonald | 175 | 26 | 24 | 0.236 | 0.303 | 0.401 | RF-LF-CF |
| Mike Aviles | 107 | 17 | 8 | 0.317 | 0.340 | 0.436 | 3B |
| Mike Cameron | 105 | 9 | 9 | 0.149 | 0.212 | 0.266 | RF |
| Drew Sutton | 60 | 11 | 7 | 0.315 | 0.362 | 0.444 | |
| Ryan Lavarnway | 43 | 5 | 8 | 0.231 | 0.302 | 0.436 | |
| Yamaico Navarro | 40 | 6 | 3 | 0.216 | 0.275 | 0.351 | 3B |
| Conor Jackson | 22 | 2 | 5 | 0.158 | 0.227 | 0.316 | |
| Jose Iglesias | 6 | 3 | 0 | 0.333 | 0.333 | 0.333 | |
| Lars Anderson | 5 | 2 | 0 | 0.000 | 0.000 | 0.000 | |
| Nate Spears | 4 | 0 | 0 | 0.000 | 0.000 | 0.000 | |
| Joey Gathright | 1 | 1 | 0 | 0.000 | 1.000 | 0.000 |
| Name | IP | ERA | Gs | Gr | SO | WHIP |
|---|---|---|---|---|---|---|
| Josh Beckett | 193.0 | 2.89 | 30 | 0 | 175 | 1.03 |
| Jon Lester | 191.3 | 3.47 | 31 | 0 | 182 | 1.26 |
| John Lackey | 160.0 | 6.41 | 28 | 0 | 108 | 1.62 |
| Tim Wakefield | 154.3 | 5.12 | 23 | 10 | 93 | 1.36 |
| Alfredo Aceves | 114.0 | 2.61 | 4 | 51 | 80 | 1.10 |
| Clay Buchholz | 82.3 | 3.48 | 14 | 0 | 60 | 1.29 |
| Daniel Bard | 73.0 | 3.33 | 0 | 70 | 74 | 0.96 |
| Andrew Miller | 65.0 | 5.54 | 12 | 5 | 50 | 1.81 |
| Matt Albers | 64.3 | 4.73 | 0 | 56 | 68 | 1.44 |
| Jonathan Papelbon | 64.0 | 2.94 | 0 | 63 | 87 | 0.93 |
| Dan Wheeler | 49.0 | 4.38 | 0 | 47 | 39 | 1.11 |
| Erik Bedard | 38.0 | 4.03 | 8 | 0 | 38 | 1.55 |
| Daisuke Matsuzaka | 37.0 | 5.30 | 7 | 1 | 26 | 1.47 |
| Franklin Morales | 32.0 | 3.62 | 0 | 36 | 31 | 1.27 |
| Scott Atchison | 30.0 | 3.26 | 0 | 17 | 17 | 1.22 |
| Kyle Weiland | 24.3 | 7.66 | 5 | 2 | 13 | 1.66 |
| Michael Bowden | 20.0 | 4.05 | 0 | 14 | 17 | 1.50 |
| Bobby Jenks | 15.3 | 6.32 | 0 | 19 | 17 | 2.23 |
| Felix Doubront | 10.0 | 6.10 | 0 | 11 | 6 | 1.94 |
| Hideki Okajima | 8.0 | 4.32 | 0 | 7 | 6 | 1.44 |
| Randy Williams | 8.0 | 6.48 | 0 | 7 | 6 | 1.80 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | 12 | 0.75 |
| Tommy Hottovy | 4.0 | 6.75 | 0 | 8 | 2 | 1.75 |
| Junichi Tazawa | 3.0 | 6.00 | 0 | 3 | 4 | 1.33 |
| Trever Miller | 2.0 | 0.00 | 0 | 3 | 1 | 0.00 |
| Dennys Reyes | 1.3 | 16.20 | 0 | 4 | 1 | 2.40 |
| Darnell McDonald | 1.0 | 18.00 | 0 | 1 | 0 | 3.00 |
_