| Name | PA | R | RBI | BA | OBP | SLG | POS |
|---|---|---|---|---|---|---|---|
| Juan Pierre | 711 | 80 | 50 | 0.279 | 0.329 | 0.327 | LF |
| Alexei Ramirez | 684 | 81 | 70 | 0.269 | 0.328 | 0.399 | SS |
| Paul Konerko | 639 | 69 | 105 | 0.300 | 0.388 | 0.517 | 1B-DH |
| Alex Rios | 570 | 64 | 44 | 0.227 | 0.265 | 0.348 | CF |
| Gordon Beckham | 557 | 60 | 44 | 0.230 | 0.296 | 0.337 | 2B |
| A.J. Pierzynski | 500 | 38 | 48 | 0.287 | 0.323 | 0.405 | CR |
| Adam Dunn | 496 | 36 | 42 | 0.159 | 0.292 | 0.277 | DH-1B |
| Carlos Quentin | 483 | 53 | 77 | 0.254 | 0.340 | 0.499 | RF-DH |
| Brent Morel | 444 | 44 | 41 | 0.245 | 0.287 | 0.366 | 3B |
| Brent Lillibridge | 216 | 38 | 29 | 0.258 | 0.340 | 0.505 | RF-1B-CF |
| Omar Vizquel | 182 | 18 | 8 | 0.251 | 0.287 | 0.305 | 3B-2B |
| Alejandro De Aza | 171 | 29 | 23 | 0.329 | 0.400 | 0.520 | RF-CF |
| Mark Teahen | 130 | 11 | 11 | 0.203 | 0.277 | 0.305 | 3B-1B |
| Tyler Flowers | 129 | 13 | 16 | 0.209 | 0.310 | 0.409 | CR |
| Dayan Viciedo | 113 | 11 | 6 | 0.255 | 0.327 | 0.314 | RF |
| Ramon Castro | 75 | 6 | 10 | 0.235 | 0.307 | 0.456 | CR |
| Dallas McPherson | 15 | 1 | 0 | 0.133 | 0.133 | 0.133 | |
| Donny Lucy | 11 | 1 | 1 | 0.200 | 0.273 | 0.300 | |
| Eduardo Escobar | 7 | 0 | 0 | 0.286 | 0.286 | 0.286 | |
| Lastings Milledge | 4 | 1 | 0 | 0.250 | 0.250 | 0.500 |
| Name | IP | ERA | Gs | Gr | SO | WHIP |
|---|---|---|---|---|---|---|
| Mark Buehrle | 205.0 | 3.59 | 31 | 0 | 109 | 1.29 |
| Gavin Floyd | 193.3 | 4.37 | 30 | 1 | 151 | 1.16 |
| John Danks | 170.0 | 4.33 | 27 | 0 | 135 | 1.34 |
| Philip Humber | 163.0 | 3.75 | 26 | 2 | 116 | 1.18 |
| Edwin Jackson | 121.3 | 3.92 | 19 | 0 | 97 | 1.42 |
| Jake Peavy | 111.3 | 4.92 | 18 | 1 | 95 | 1.26 |
| Chris Sale | 71.0 | 2.79 | 0 | 58 | 79 | 1.11 |
| Jesse Crain | 65.0 | 2.62 | 0 | 67 | 70 | 1.24 |
| Sergio Santos | 63.0 | 3.55 | 0 | 63 | 92 | 1.10 |
| Matt Thornton | 59.3 | 3.32 | 0 | 62 | 63 | 1.36 |
| Will Ohman | 53.0 | 4.22 | 0 | 59 | 54 | 1.31 |
| Zach Stewart | 50.3 | 6.22 | 8 | 2 | 35 | 1.52 |
| Tony Pena | 20.0 | 6.20 | 0 | 17 | 17 | 1.72 |
| Brian Bruney | 19.3 | 6.86 | 0 | 23 | 16 | 1.93 |
| Dylan Axelrod | 18.3 | 2.89 | 3 | 1 | 19 | 1.45 |
| Jason Frasor | 17.3 | 5.09 | 0 | 20 | 20 | 1.75 |
| Josh Kinney | 17.3 | 6.62 | 0 | 13 | 20 | 1.70 |
| Jeff Gray | 13.0 | 2.70 | 0 | 6 | 7 | 1.27 |
| Addison Reed | 7.0 | 3.68 | 0 | 6 | 12 | 1.50 |
| Shane Lindsay | 6.0 | 12.00 | 0 | 4 | 6 | 2.67 |
| Hector Santiago | 5.0 | 0.00 | 0 | 2 | 2 | 0.38 |
| Lucas Harrell | 5.0 | 7.20 | 0 | 3 | 5 | 2.40 |
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