| Name | PA | R | RBI | BA | OBP | SLG | POS |
|---|---|---|---|---|---|---|---|
| Ian Kinsler | 723 | 121 | 77 | 0.255 | 0.355 | 0.477 | 2B-DH |
| Michael Young | 689 | 88 | 106 | 0.338 | 0.380 | 0.474 | DH-3B-1B-2B |
| Elvis Andrus | 665 | 96 | 60 | 0.279 | 0.347 | 0.361 | SS |
| Josh Hamilton | 538 | 80 | 94 | 0.298 | 0.346 | 0.536 | LF-CF |
| Adrian Beltre | 525 | 82 | 105 | 0.296 | 0.331 | 0.561 | 3B-DH |
| Nelson Cruz | 513 | 64 | 87 | 0.263 | 0.312 | 0.509 | RF-LF |
| Mitch Moreland | 512 | 60 | 51 | 0.259 | 0.320 | 0.414 | 1B-RF |
| David Murphy | 440 | 46 | 46 | 0.275 | 0.328 | 0.401 | LF-RF-CF |
| Mike Napoli | 432 | 72 | 75 | 0.320 | 0.414 | 0.631 | CR-1B-DH |
| Yorvit Torrealba | 419 | 40 | 37 | 0.273 | 0.306 | 0.399 | CR-DH |
| Endy Chavez | 274 | 37 | 27 | 0.301 | 0.323 | 0.426 | CF-LF |
| Craig Gentry | 153 | 26 | 13 | 0.271 | 0.347 | 0.346 | CF |
| Julio Borbon | 98 | 10 | 11 | 0.270 | 0.305 | 0.348 | CF |
| Andres Blanco | 82 | 9 | 3 | 0.224 | 0.263 | 0.342 | SS |
| Chris Davis | 81 | 9 | 6 | 0.250 | 0.296 | 0.408 | 1B |
| Taylor Teagarden | 36 | 3 | 2 | 0.235 | 0.278 | 0.294 | CR |
| Omar Quintanilla | 23 | 3 | 2 | 0.045 | 0.045 | 0.136 | |
| Esteban German | 13 | 6 | 4 | 0.455 | 0.462 | 0.818 | |
| Matt Treanor | 12 | 0 | 1 | 0.000 | 0.083 | 0.000 | |
| Leonys Martin | 8 | 2 | 0 | 0.375 | 0.375 | 0.500 |
| Name | IP | ERA | Gs | Gr | SO | WHIP |
|---|---|---|---|---|---|---|
| C.J. Wilson | 223.0 | 2.94 | 34 | 0 | 206 | 1.19 |
| Colby Lewis | 200.0 | 4.40 | 32 | 0 | 169 | 1.21 |
| Derek Holland | 198.0 | 3.95 | 32 | 0 | 162 | 1.35 |
| Matt Harrison | 185.3 | 3.39 | 30 | 1 | 126 | 1.28 |
| Alexi Ogando | 169.0 | 3.51 | 29 | 2 | 126 | 1.14 |
| Neftali Feliz | 62.0 | 2.74 | 0 | 64 | 54 | 1.16 |
| Darren Oliver | 51.0 | 2.29 | 0 | 61 | 44 | 1.14 |
| Mark Lowe | 45.0 | 3.80 | 0 | 52 | 42 | 1.44 |
| Yoshinori Tateyama | 44.0 | 4.50 | 0 | 39 | 43 | 1.09 |
| Dave Bush | 37.0 | 5.79 | 3 | 14 | 23 | 1.50 |
| Scott Feldman | 32.0 | 3.94 | 2 | 9 | 22 | 1.09 |
| Michael Kirkman | 27.0 | 6.59 | 0 | 15 | 21 | 1.39 |
| Mike Adams | 25.3 | 2.10 | 0 | 27 | 25 | 0.90 |
| Arthur Rhodes | 24.0 | 4.81 | 0 | 32 | 15 | 1.48 |
| Koji Uehara | 18.0 | 4.00 | 0 | 22 | 23 | 0.78 |
| Brett Tomko | 17.3 | 4.58 | 0 | 8 | 14 | 1.42 |
| Darren O'Day | 16.3 | 5.40 | 0 | 16 | 18 | 1.32 |
| Tommy Hunter | 15.0 | 2.93 | 0 | 8 | 10 | 1.11 |
| Pedro Strop | 9.3 | 3.72 | 0 | 11 | 9 | 1.45 |
| Cody Eppley | 9.0 | 8.00 | 0 | 10 | 6 | 1.78 |
| Mark Hamburger | 8.0 | 4.50 | 0 | 5 | 6 | 1.00 |
| Mike Gonzalez | 7.0 | 5.14 | 0 | 7 | 5 | 1.14 |
| Mason Tobin | 5.0 | 6.75 | 0 | 4 | 0 | 1.88 |
| Ryan Tucker | 5.0 | 7.20 | 0 | 5 | 4 | 2.00 |
| Merkin Valdez | 4.0 | 6.23 | 0 | 5 | 6 | 1.85 |
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