| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 206 | 24 | 10 | 0.238 | 0.354 | -0.93 | 2B |
| Adrian Gonzalez | 203 | 28 | 42 | 0.328 | 0.379 | 2.92 | 1B |
| Jacoby Ellsbury | 195 | 28 | 22 | 0.294 | 0.349 | 0.99 | CF |
| Carl Crawford | 183 | 16 | 13 | 0.213 | 0.246 | -0.95 | LF |
| David Ortiz | 181 | 24 | 22 | 0.294 | 0.370 | 0.88 | DH |
| Kevin Youkilis | 179 | 28 | 30 | 0.280 | 0.413 | 2.18 | 3B |
| Jed Lowrie | 148 | 21 | 19 | 0.316 | 0.358 | 0.97 | SS-3B |
| J.D. Drew | 142 | 12 | 10 | 0.239 | 0.366 | -0.79 | RF |
| Jarrod Saltalamacchia | 96 | 8 | 11 | 0.236 | 0.292 | -0.10 | CR |
| Marco Scutaro | 76 | 4 | 8 | 0.235 | 0.316 | -0.40 | SS |
| Jason Varitek | 75 | 5 | 5 | 0.197 | 0.280 | -0.59 | CR |
| Mike Cameron | 52 | 5 | 4 | 0.152 | 0.231 | -0.19 | CF |
| Darnell McDonald | 22 | 1 | 1 | 0.150 | 0.227 | -0.27 | RF-LF-CF |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 63.7 | 3.68 | 10 | 0 | X | 0.20 |
| Josh Beckett | 57.3 | 1.73 | 9 | 0 | X | 2.79 |
| Clay Buchholz | 52.7 | 3.42 | 9 | 0 | X | 0.48 |
| John Lackey | 39.3 | 8.01 | 7 | 0 | X | -3.85 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.30 |
| Tim Wakefield | 23.3 | 5.40 | 2 | 9 | X | -0.87 |
| Daniel Bard | 23.0 | 3.52 | 0 | 22 | X | 0.15 |
| Alfredo Aceves | 22.3 | 2.42 | 1 | 11 | X | 0.73 |
| Jonathan Papelbon | 18.7 | 2.41 | 0 | 18 | X | 0.61 |
| Matt Albers | 17.3 | 4.15 | 0 | 13 | X | -0.14 |
| Dan Wheeler | 11.7 | 10.80 | 0 | 12 | X | -1.90 |
| Bobby Jenks | 8.7 | 9.35 | 0 | 11 | X | -1.12 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.10 |
| Scott Atchison | 8.3 | 4.32 | 0 | 3 | X | -0.10 |
| Rich Hill | 5.3 | 0.00 | 0 | 5 | X | 0.47 |
| Felix Doubront | 2.7 | 6.75 | 0 | 3 | X | -0.18 |
| Franklin Morales | 2.0 | 0.00 | 0 | 1 | X | 0.18 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
_