| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adrian Gonzalez | 221 | 31 | 44 | 0.340 | 0.389 | 3.06 | 1B |
| Dustin Pedroia | 220 | 26 | 14 | 0.249 | 0.359 | -0.59 | 2B |
| Jacoby Ellsbury | 213 | 30 | 23 | 0.294 | 0.357 | 0.92 | CF |
| David Ortiz | 199 | 26 | 23 | 0.303 | 0.372 | 0.81 | DH |
| Carl Crawford | 199 | 22 | 16 | 0.228 | 0.261 | -0.35 | LF |
| Kevin Youkilis | 191 | 29 | 32 | 0.275 | 0.408 | 2.24 | 3B |
| Jed Lowrie | 166 | 23 | 21 | 0.300 | 0.343 | 1.00 | SS-3B |
| J.D. Drew | 150 | 12 | 10 | 0.232 | 0.353 | -0.96 | RF |
| Jarrod Saltalamacchia | 108 | 11 | 15 | 0.240 | 0.296 | 0.38 | CR |
| Jason Varitek | 79 | 6 | 7 | 0.203 | 0.291 | -0.36 | CR |
| Marco Scutaro | 76 | 4 | 8 | 0.235 | 0.316 | -0.40 | SS |
| Mike Cameron | 61 | 6 | 6 | 0.170 | 0.230 | -0.07 | CF |
| Darnell McDonald | 23 | 1 | 1 | 0.143 | 0.217 | -0.29 | RF-LF-CF |
| Drew Sutton | 9 | 2 | 1 | 0.333 | 0.333 | 0.12 | X |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 69.7 | 3.36 | 11 | 0 | X | 0.73 |
| Josh Beckett | 64.0 | 1.69 | 10 | 0 | X | 3.17 |
| Clay Buchholz | 60.0 | 3.30 | 10 | 0 | X | 0.71 |
| John Lackey | 39.3 | 8.01 | 7 | 0 | X | -3.85 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.30 |
| Tim Wakefield | 30.0 | 4.50 | 3 | 9 | X | -0.48 |
| Daniel Bard | 24.7 | 3.65 | 0 | 24 | X | 0.09 |
| Alfredo Aceves | 22.3 | 2.42 | 1 | 11 | X | 0.73 |
| Jonathan Papelbon | 20.7 | 2.61 | 0 | 20 | X | 0.58 |
| Matt Albers | 17.3 | 4.15 | 0 | 13 | X | -0.14 |
| Dan Wheeler | 12.7 | 9.95 | 0 | 13 | X | -1.81 |
| Scott Atchison | 9.3 | 3.86 | 0 | 4 | X | -0.01 |
| Bobby Jenks | 8.7 | 9.35 | 0 | 11 | X | -1.12 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.10 |
| Rich Hill | 7.0 | 0.00 | 0 | 7 | X | 0.62 |
| Franklin Morales | 3.0 | 6.00 | 0 | 2 | X | -0.15 |
| Felix Doubront | 2.7 | 6.75 | 0 | 3 | X | -0.18 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
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