| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adrian Gonzalez | 243 | 34 | 47 | 0.332 | 0.379 | 3.14 | 1B |
| Dustin Pedroia | 243 | 29 | 18 | 0.243 | 0.350 | -0.43 | 2B |
| Jacoby Ellsbury | 236 | 36 | 27 | 0.296 | 0.364 | 1.40 | CF |
| Carl Crawford | 219 | 25 | 21 | 0.231 | 0.265 | -0.01 | LF |
| David Ortiz | 217 | 30 | 24 | 0.306 | 0.378 | 0.88 | DH |
| Kevin Youkilis | 212 | 31 | 34 | 0.260 | 0.387 | 2.14 | 3B |
| Jed Lowrie | 174 | 23 | 21 | 0.306 | 0.351 | 0.78 | SS-3B |
| J.D. Drew | 157 | 12 | 10 | 0.235 | 0.350 | -1.16 | RF |
| Jarrod Saltalamacchia | 119 | 12 | 15 | 0.218 | 0.277 | 0.21 | CR |
| Jason Varitek | 87 | 6 | 7 | 0.208 | 0.287 | -0.56 | CR |
| Marco Scutaro | 76 | 4 | 8 | 0.235 | 0.316 | -0.42 | SS |
| Mike Cameron | 65 | 7 | 7 | 0.196 | 0.262 | 0.03 | CF |
| Drew Sutton | 25 | 4 | 3 | 0.208 | 0.200 | 0.18 | X |
| Darnell McDonald | 23 | 1 | 1 | 0.143 | 0.217 | -0.30 | RF-LF-CF |
| Josh Reddick | 9 | 2 | 3 | 0.500 | 0.556 | 0.33 | RF-LF |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 75.3 | 3.94 | 12 | 0 | X | -0.11 |
| Josh Beckett | 70.0 | 1.80 | 11 | 0 | X | 3.39 |
| Clay Buchholz | 66.0 | 3.41 | 11 | 0 | X | 0.72 |
| John Lackey | 39.3 | 8.01 | 7 | 0 | X | -3.79 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.24 |
| Tim Wakefield | 37.0 | 4.14 | 4 | 9 | X | -0.22 |
| Alfredo Aceves | 28.3 | 2.22 | 2 | 11 | X | 1.09 |
| Daniel Bard | 25.7 | 3.51 | 0 | 25 | X | 0.22 |
| Jonathan Papelbon | 22.7 | 2.78 | 0 | 22 | X | 0.58 |
| Matt Albers | 20.3 | 3.54 | 0 | 15 | X | 0.16 |
| Dan Wheeler | 14.0 | 9.00 | 0 | 14 | X | -1.67 |
| Scott Atchison | 10.3 | 4.35 | 0 | 5 | X | -0.12 |
| Bobby Jenks | 8.7 | 9.35 | 0 | 11 | X | -1.11 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.09 |
| Rich Hill | 8.0 | 0.00 | 0 | 8 | X | 0.72 |
| Franklin Morales | 3.0 | 6.00 | 0 | 2 | X | -0.15 |
| Felix Doubront | 2.7 | 6.75 | 0 | 3 | X | -0.18 |
| Michael Bowden | 2.0 | 0.00 | 0 | 1 | X | 0.18 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
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