| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adrian Gonzalez | 289 | 43 | 59 | 0.338 | 0.391 | 4.43 | 1B |
| Dustin Pedroia | 286 | 34 | 26 | 0.263 | 0.374 | 0.08 | 2B |
| Jacoby Ellsbury | 286 | 46 | 33 | 0.315 | 0.371 | 2.08 | CF |
| Carl Crawford | 263 | 32 | 31 | 0.245 | 0.278 | 0.90 | LF |
| David Ortiz | 260 | 42 | 39 | 0.325 | 0.396 | 2.85 | DH |
| Kevin Youkilis | 255 | 38 | 38 | 0.255 | 0.380 | 2.43 | 3B |
| Jed Lowrie | 212 | 27 | 25 | 0.276 | 0.325 | 0.85 | SS-3B |
| J.D. Drew | 186 | 15 | 16 | 0.234 | 0.339 | -0.79 | RF |
| Jarrod Saltalamacchia | 142 | 17 | 18 | 0.237 | 0.296 | 0.59 | CR |
| Jason Varitek | 108 | 14 | 13 | 0.234 | 0.324 | 0.49 | CR |
| Marco Scutaro | 96 | 10 | 9 | 0.273 | 0.333 | -0.09 | SS |
| Mike Cameron | 85 | 9 | 8 | 0.160 | 0.224 | -0.06 | CF |
| Drew Sutton | 31 | 5 | 5 | 0.267 | 0.258 | 0.38 | X |
| Darnell McDonald | 23 | 1 | 1 | 0.143 | 0.217 | -0.29 | RF-LF-CF |
| Josh Reddick | 15 | 3 | 4 | 0.385 | 0.400 | 0.41 | RF-LF |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Josh Beckett | 83.0 | 2.06 | 13 | 0 | X | 3.48 |
| Jon Lester | 81.3 | 3.98 | 13 | 0 | X | -0.24 |
| Clay Buchholz | 77.7 | 3.59 | 13 | 0 | X | 0.48 |
| John Lackey | 51.0 | 7.41 | 9 | 0 | X | -4.23 |
| Tim Wakefield | 48.3 | 4.84 | 6 | 9 | X | -1.11 |
| Alfredo Aceves | 41.0 | 3.29 | 3 | 13 | X | 0.54 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.26 |
| Daniel Bard | 32.3 | 2.78 | 0 | 31 | X | 0.81 |
| Jonathan Papelbon | 27.0 | 4.33 | 0 | 27 | X | -0.30 |
| Matt Albers | 24.0 | 3.38 | 0 | 20 | X | 0.27 |
| Dan Wheeler | 18.0 | 7.50 | 0 | 18 | X | -1.53 |
| Scott Atchison | 13.3 | 4.72 | 0 | 7 | X | -0.27 |
| Bobby Jenks | 12.3 | 6.57 | 0 | 14 | X | -0.78 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.09 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.72 |
| Michael Bowden | 3.0 | 0.00 | 0 | 2 | X | 0.27 |
| Franklin Morales | 3.0 | 6.00 | 0 | 2 | X | -0.15 |
| Felix Doubront | 2.7 | 6.75 | 0 | 3 | X | -0.18 |
| Tommy Hottovy | 2.3 | 0.00 | 0 | 4 | X | 0.21 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
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