| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Juan Pierre | 300 | 31 | 14 | 0.258 | 0.313 | -2.05 | LF |
| Alexei Ramirez | 287 | 42 | 34 | 0.293 | 0.355 | 1.50 | SS |
| Paul Konerko | 282 | 33 | 52 | 0.322 | 0.390 | 2.56 | 1B-DH |
| Carlos Quentin | 274 | 37 | 46 | 0.269 | 0.369 | 2.53 | RF-DH |
| Alex Rios | 254 | 30 | 15 | 0.212 | 0.264 | -1.01 | CF |
| Adam Dunn | 245 | 20 | 29 | 0.180 | 0.322 | -0.39 | DH-1B |
| Gordon Beckham | 234 | 29 | 21 | 0.240 | 0.303 | -0.03 | 2B |
| A.J. Pierzynski | 227 | 17 | 19 | 0.280 | 0.317 | -1.35 | CR |
| Brent Morel | 155 | 14 | 13 | 0.252 | 0.265 | -0.67 | 3B |
| Brent Lillibridge | 106 | 14 | 12 | 0.273 | 0.368 | 0.34 | RF-1B-CF |
| Omar Vizquel | 94 | 9 | 8 | 0.276 | 0.309 | -0.34 | 3B-2B |
| Mark Teahen | 67 | 6 | 4 | 0.203 | 0.299 | -0.46 | X |
| Ramon Castro | 58 | 5 | 7 | 0.222 | 0.276 | -0.05 | CR |
| Dallas McPherson | 15 | 1 | 0 | 0.133 | 0.133 | -0.23 | X |
| Lastings Milledge | 4 | 1 | 0 | 0.250 | 0.250 | 0.01 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Mark Buehrle | 86.7 | 3.84 | 13 | 0 | X | 0.02 |
| John Danks | 85.3 | 4.54 | 13 | 0 | X | -1.36 |
| Philip Humber | 82.3 | 2.95 | 12 | 2 | X | 1.73 |
| Gavin Floyd | 81.0 | 3.89 | 12 | 1 | X | -0.07 |
| Edwin Jackson | 80.0 | 4.39 | 13 | 0 | X | -1.00 |
| Sergio Santos | 31.7 | 3.41 | 0 | 26 | X | 0.33 |
| Jake Peavy | 29.0 | 4.66 | 5 | 0 | X | -0.54 |
| Jesse Crain | 29.0 | 3.41 | 0 | 28 | X | 0.30 |
| Chris Sale | 25.3 | 4.62 | 0 | 24 | X | -0.45 |
| Matt Thornton | 23.3 | 4.63 | 0 | 25 | X | -0.42 |
| Tony Pena | 20.3 | 6.20 | 0 | 17 | X | -1.11 |
| Will Ohman | 17.0 | 5.82 | 0 | 21 | X | -0.78 |
| Jeff Gray | 13.3 | 2.70 | 0 | 6 | X | 0.36 |
| Brian Bruney | 4.3 | 4.15 | 0 | 5 | X | -0.03 |
| Lucas Harrell | 4.3 | 8.31 | 0 | 2 | X | -0.45 |
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