| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adrian Gonzalez | 325 | 54 | 68 | 0.353 | 0.406 | 5.78 | 1B |
| Dustin Pedroia | 325 | 45 | 33 | 0.268 | 0.378 | 1.16 | 2B |
| Jacoby Ellsbury | 321 | 52 | 37 | 0.310 | 0.371 | 2.40 | CF |
| David Ortiz | 296 | 49 | 48 | 0.323 | 0.402 | 3.78 | DH |
| Kevin Youkilis | 290 | 45 | 52 | 0.265 | 0.386 | 3.91 | 3B |
| Carl Crawford | 278 | 33 | 31 | 0.242 | 0.273 | 0.71 | LF |
| Jed Lowrie | 216 | 27 | 25 | 0.270 | 0.319 | 0.79 | SS-3B |
| J.D. Drew | 209 | 19 | 18 | 0.235 | 0.335 | -0.63 | RF |
| Jarrod Saltalamacchia | 162 | 18 | 20 | 0.248 | 0.309 | 0.49 | CR |
| Marco Scutaro | 125 | 14 | 13 | 0.286 | 0.352 | 0.13 | SS |
| Jason Varitek | 120 | 16 | 15 | 0.231 | 0.325 | 0.66 | CR |
| Mike Cameron | 96 | 9 | 9 | 0.153 | 0.219 | -0.19 | CF |
| Darnell McDonald | 38 | 3 | 3 | 0.114 | 0.184 | -0.19 | RF-LF-CF |
| Drew Sutton | 36 | 6 | 5 | 0.314 | 0.306 | 0.38 | X |
| Josh Reddick | 21 | 5 | 6 | 0.412 | 0.476 | 0.70 | RF-LF |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 97.3 | 3.70 | 15 | 0 | X | 0.32 |
| Josh Beckett | 92.0 | 1.86 | 14 | 0 | X | 4.26 |
| Clay Buchholz | 82.7 | 3.48 | 14 | 0 | X | 0.69 |
| Tim Wakefield | 63.3 | 4.26 | 8 | 9 | X | -0.62 |
| John Lackey | 59.0 | 7.02 | 10 | 0 | X | -4.37 |
| Alfredo Aceves | 43.7 | 3.30 | 3 | 15 | X | 0.55 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.27 |
| Daniel Bard | 33.7 | 2.67 | 0 | 32 | X | 0.92 |
| Jonathan Papelbon | 28.0 | 4.18 | 0 | 28 | X | -0.22 |
| Matt Albers | 26.3 | 3.08 | 0 | 22 | X | 0.47 |
| Dan Wheeler | 19.3 | 6.98 | 0 | 20 | X | -1.42 |
| Scott Atchison | 13.3 | 4.72 | 0 | 7 | X | -0.28 |
| Bobby Jenks | 12.3 | 6.57 | 0 | 14 | X | -0.78 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.09 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.72 |
| Andrew Miller | 5.7 | 4.76 | 1 | 0 | X | -0.12 |
| Michael Bowden | 5.3 | 1.69 | 0 | 5 | X | 0.27 |
| Tommy Hottovy | 3.7 | 7.36 | 0 | 7 | X | -0.30 |
| Franklin Morales | 3.0 | 6.00 | 0 | 2 | X | -0.15 |
| Felix Doubront | 2.7 | 6.75 | 0 | 3 | X | -0.18 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
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