| Name | PA | R | RBI | BA | OBP | SLG | POS |
|---|---|---|---|---|---|---|---|
| Adam Dunn | 649 | 87 | 96 | 0.204 | 0.333 | 0.468 | DH-1B |
| Alex Rios | 640 | 93 | 91 | 0.304 | 0.334 | 0.516 | RF |
| Alexei Ramirez | 621 | 59 | 73 | 0.265 | 0.287 | 0.364 | SS |
| Paul Konerko | 598 | 66 | 75 | 0.298 | 0.371 | 0.486 | 1B-DH |
| Alejandro De Aza | 585 | 81 | 50 | 0.281 | 0.349 | 0.410 | CF-LF |
| Gordon Beckham | 582 | 62 | 60 | 0.234 | 0.296 | 0.371 | 2B |
| Dayan Viciedo | 543 | 64 | 78 | 0.255 | 0.300 | 0.444 | LF-DH |
| A.J. Pierzynski | 520 | 68 | 77 | 0.278 | 0.326 | 0.501 | CR |
| Kevin Youkilis | 344 | 47 | 46 | 0.236 | 0.346 | 0.425 | 3B-1B |
| Dewayne Wise | 176 | 20 | 22 | 0.258 | 0.295 | 0.405 | CF-LF |
| Tyler Flowers | 153 | 19 | 13 | 0.213 | 0.296 | 0.412 | CR |
| Orlando Hudson | 152 | 10 | 17 | 0.197 | 0.262 | 0.307 | 3B-2B |
| Brent Morel | 125 | 14 | 5 | 0.177 | 0.225 | 0.195 | 3B |
| Eduardo Escobar | 97 | 14 | 3 | 0.207 | 0.281 | 0.276 | 3B |
| Jordan Danks | 75 | 12 | 4 | 0.224 | 0.280 | 0.284 | LF-CF |
| Brent Lillibridge | 70 | 10 | 2 | 0.175 | 0.232 | 0.190 | 1B-LF |
| Kosuke Fukudome | 51 | 2 | 4 | 0.171 | 0.294 | 0.195 | LF |
| Ray Olmedo | 42 | 8 | 1 | 0.244 | 0.244 | 0.293 | 3B |
| Dan Johnson | 31 | 8 | 6 | 0.364 | 0.548 | 0.818 | |
| Jose Lopez | 24 | 2 | 0 | 0.217 | 0.250 | 0.261 | 3B |
| Hector Gimenez | 11 | 1 | 1 | 0.455 | 0.455 | 0.455 |
| Name | IP | ERA | Gs | Gr | SO | WHIP |
|---|---|---|---|---|---|---|
| Jake Peavy | 219.0 | 3.37 | 32 | 0 | 194 | 1.10 |
| Chris Sale | 192.0 | 3.05 | 29 | 1 | 192 | 1.14 |
| Gavin Floyd | 168.0 | 4.29 | 29 | 0 | 144 | 1.36 |
| Jose Quintana | 136.0 | 3.76 | 22 | 3 | 81 | 1.35 |
| Philip Humber | 102.0 | 6.44 | 16 | 10 | 85 | 1.54 |
| Nate Jones | 71.3 | 2.39 | 0 | 65 | 65 | 1.38 |
| Hector Santiago | 70.0 | 3.33 | 4 | 38 | 79 | 1.34 |
| Matt Thornton | 65.0 | 3.46 | 0 | 74 | 53 | 1.23 |
| Francisco Liriano | 56.3 | 5.40 | 11 | 1 | 58 | 1.52 |
| Addison Reed | 55.0 | 4.75 | 0 | 62 | 54 | 1.36 |
| John Danks | 53.3 | 5.70 | 9 | 0 | 30 | 1.49 |
| Dylan Axelrod | 51.0 | 5.47 | 7 | 7 | 40 | 1.51 |
| Jesse Crain | 48.0 | 2.44 | 0 | 51 | 60 | 1.08 |
| Brett Myers | 34.3 | 3.12 | 0 | 35 | 21 | 1.12 |
| Zach Stewart | 30.0 | 6.00 | 1 | 17 | 16 | 1.50 |
| Will Ohman | 26.3 | 6.41 | 0 | 32 | 13 | 1.05 |
| Brian Omogrosso | 21.0 | 2.57 | 0 | 17 | 18 | 1.38 |
| Leyson Septimo | 14.0 | 5.02 | 0 | 21 | 14 | 0.98 |
| Donnie Veal | 13.0 | 1.38 | 0 | 24 | 19 | 0.69 |
| Eric Stults | 6.3 | 2.70 | 1 | 1 | 4 | 1.50 |
| Pedro Hernandez | 4.0 | 18.00 | 1 | 0 | 2 | 3.25 |
| Jhan Marinez | 2.3 | 0.00 | 0 | 2 | 1 | 1.50 |
| Deunte Heath | 2.0 | 4.50 | 0 | 3 | 1 | 1.00 |
| Brian Bruney | 1.0 | 0.00 | 0 | 1 | 2 | 2.00 |
| Dewayne Wise | 1.0 | 0.00 | 0 | 1 | 0 | 2.00 |
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