| Name | PA | R | RBI | BA | OBP | SLG | POS |
|---|---|---|---|---|---|---|---|
| Starlin Castro | 691 | 78 | 78 | 0.283 | 0.323 | 0.430 | SS |
| Alfonso Soriano | 615 | 68 | 108 | 0.262 | 0.322 | 0.499 | LF |
| Darwin Barney | 588 | 73 | 44 | 0.254 | 0.299 | 0.354 | 2B |
| David DeJesus | 582 | 76 | 50 | 0.263 | 0.350 | 0.403 | RF-CF |
| Bryan LaHair | 380 | 42 | 40 | 0.259 | 0.334 | 0.450 | 1B-RF |
| Anthony Rizzo | 368 | 44 | 48 | 0.285 | 0.342 | 0.463 | 1B |
| Luis Valbuena | 303 | 26 | 28 | 0.219 | 0.310 | 0.340 | 3B |
| Joe Mather | 243 | 18 | 19 | 0.209 | 0.256 | 0.324 | CF-LF-3B-RF |
| Steve Clevenger | 215 | 16 | 16 | 0.201 | 0.260 | 0.276 | CR |
| Ian Stewart | 202 | 16 | 17 | 0.201 | 0.292 | 0.335 | 3B |
| Geovany Soto | 197 | 26 | 14 | 0.199 | 0.284 | 0.347 | CR |
| Tony Campana | 192 | 26 | 5 | 0.264 | 0.308 | 0.299 | CF-LF |
| Welington Castillo | 190 | 16 | 22 | 0.265 | 0.337 | 0.418 | CR |
| Reed Johnson | 183 | 23 | 16 | 0.302 | 0.355 | 0.444 | RF-CF-LF |
| Jeff Baker | 144 | 16 | 20 | 0.269 | 0.306 | 0.448 | 1B-RF |
| Brett Jackson | 142 | 14 | 9 | 0.175 | 0.303 | 0.342 | CF |
| Josh Vitters | 109 | 7 | 5 | 0.121 | 0.193 | 0.202 | 3B |
| Dave Sappelt | 78 | 8 | 8 | 0.275 | 0.351 | 0.449 | RF |
| Adrian Cardenas | 67 | 5 | 2 | 0.183 | 0.269 | 0.283 | 2B |
| Marlon Byrd | 47 | 1 | 2 | 0.070 | 0.149 | 0.070 | CF |
| Koyie Hill | 39 | 3 | 1 | 0.179 | 0.179 | 0.205 | CR |
| Blake DeWitt | 30 | 1 | 1 | 0.138 | 0.133 | 0.172 | |
| Anthony Recker | 21 | 1 | 4 | 0.167 | 0.286 | 0.389 | |
| Blake Lalli | 16 | 1 | 2 | 0.133 | 0.188 | 0.133 |
| Name | IP | ERA | Gs | Gr | SO | WHIP |
|---|---|---|---|---|---|---|
| Jeff Samardzija | 174.3 | 3.81 | 28 | 0 | 180 | 1.22 |
| Travis Wood | 156.0 | 4.27 | 26 | 0 | 119 | 1.20 |
| Paul Maholm | 120.0 | 3.74 | 20 | 1 | 81 | 1.24 |
| Chris Volstad | 111.0 | 6.31 | 21 | 0 | 61 | 1.62 |
| Ryan Dempster | 104.0 | 2.25 | 16 | 0 | 83 | 1.04 |
| Matt Garza | 103.3 | 3.91 | 18 | 0 | 96 | 1.18 |
| Shawn Camp | 77.3 | 3.59 | 0 | 80 | 54 | 1.29 |
| James Russell | 69.0 | 3.25 | 0 | 77 | 55 | 1.30 |
| Justin Germano | 64.0 | 6.75 | 12 | 1 | 45 | 1.56 |
| Carlos Marmol | 55.0 | 3.42 | 0 | 61 | 72 | 1.54 |
| Manny Corpas | 46.3 | 5.01 | 0 | 48 | 28 | 1.41 |
| Rafael Dolis | 38.0 | 6.39 | 0 | 34 | 24 | 1.66 |
| Michael Bowden | 36.3 | 2.95 | 0 | 30 | 29 | 1.25 |
| Chris Rusin | 29.3 | 6.37 | 7 | 0 | 21 | 1.65 |
| Randy Wells | 28.3 | 5.34 | 4 | 8 | 14 | 2.06 |
| Casey Coleman | 24.0 | 7.40 | 1 | 16 | 16 | 2.01 |
| Brooks Raley | 24.0 | 8.14 | 5 | 0 | 16 | 1.81 |
| Alberto Cabrera | 21.3 | 5.40 | 0 | 25 | 27 | 1.57 |
| Scott Maine | 20.3 | 4.79 | 0 | 21 | 26 | 1.40 |
| Jason Berken | 18.3 | 4.82 | 4 | 0 | 11 | 1.55 |
| Jeff Beliveau | 17.3 | 4.58 | 0 | 22 | 17 | 1.87 |
| Lendy Castillo | 16.0 | 7.88 | 0 | 13 | 13 | 2.25 |
| Jairo Asencio | 14.3 | 3.07 | 0 | 12 | 8 | 1.57 |
| Jaye Chapman | 12.0 | 3.75 | 0 | 14 | 12 | 1.50 |
| Kerry Wood | 8.3 | 8.31 | 0 | 10 | 6 | 2.19 |
| Rodrigo Lopez | 6.0 | 5.68 | 0 | 4 | 2 | 2.05 |
| Blake Parker | 6.0 | 6.00 | 0 | 7 | 6 | 2.50 |
| Miguel Socolovich | 6.0 | 4.50 | 0 | 6 | 6 | 1.17 |
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