| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Alejandro de Aza | 402 | 59 | 35 | 0.277 | 0.341 | 0.51 | CF-LF |
| Adam Dunn | 395 | 54 | 66 | 0.208 | 0.357 | 3.40 | DH-1B |
| Alex Rios | 368 | 52 | 53 | 0.313 | 0.348 | 2.45 | RF |
| Alexei Ramirez | 365 | 34 | 43 | 0.267 | 0.285 | -0.42 | SS |
| Gordon Beckham | 356 | 42 | 38 | 0.235 | 0.289 | 0.11 | 2B |
| Paul Konerko | 352 | 46 | 44 | 0.325 | 0.403 | 1.25 | 1B-DH |
| Dayan Viciedo | 312 | 39 | 43 | 0.259 | 0.298 | 1.34 | LF-DH |
| A.J. Pierzynski | 310 | 41 | 50 | 0.289 | 0.339 | 2.34 | CR |
| Brent Morel | 125 | 14 | 5 | 0.174 | 0.216 | -0.92 | 3B |
| Orlando Hudson | 113 | 7 | 11 | 0.178 | 0.239 | -0.74 | 2B |
| Eduardo Escobar | 89 | 11 | 2 | 0.203 | 0.281 | -0.71 | X |
| Kevin Youkilis | 86 | 14 | 18 | 0.315 | 0.407 | 1.36 | 3B-1B |
| Tyler Flowers | 72 | 9 | 2 | 0.154 | 0.236 | -0.52 | CR |
| Brent Lillibridge | 70 | 6 | 2 | 0.175 | 0.229 | -0.79 | SS-3B |
| Kosuke Fukudome | 51 | 2 | 4 | 0.171 | 0.294 | -0.56 | LF |
| Jordan Danks | 24 | 2 | 2 | 0.348 | 0.333 | -0.14 | LF-CF |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jake Peavy | 127.0 | 3.12 | 18 | 0 | X | 2.49 |
| Chris Sale | 110.7 | 2.11 | 16 | 1 | X | 4.76 |
| Gavin Floyd | 103.0 | 4.54 | 17 | 0 | X | -1.41 |
| Philip Humber | 73.3 | 5.77 | 13 | 0 | X | -3.10 |
| Jose Quintana | 70.3 | 2.30 | 10 | 2 | X | 2.72 |
| John Danks | 53.7 | 5.70 | 9 | 0 | X | -2.18 |
| Nate Jones | 40.3 | 3.57 | 0 | 35 | X | 0.36 |
| Matt Thornton | 39.7 | 3.86 | 0 | 44 | X | 0.09 |
| Dylan Axelrod | 37.3 | 5.30 | 6 | 3 | X | -1.17 |
| Hector Santiago | 34.7 | 4.15 | 0 | 29 | X | -0.16 |
| Addison Reed | 34.0 | 3.97 | 0 | 38 | X | -0.01 |
| Zach Stewart | 30.0 | 6.00 | 1 | 17 | X | -1.43 |
| Will Ohman | 26.7 | 6.41 | 0 | 32 | X | -1.53 |
| Jesse Crain | 22.7 | 2.38 | 0 | 24 | X | 0.83 |
| Eric Stults | 6.7 | 4.05 | 1 | 1 | X | -0.01 |
| Brian Omogrosso | 6.0 | 4.50 | 0 | 4 | X | -0.08 |
| Leyson Septimo | 6.0 | 6.00 | 0 | 7 | X | -0.29 |
| Pedro Hernandez | 4.0 | 18.00 | 1 | 0 | X | -1.31 |
| Jhan Marinez | 1.7 | 0.00 | 0 | 1 | X | 0.15 |
| Brian Bruney | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
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