| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adrian Gonzalez | 491 | 63 | 80 | 0.307 | 0.352 | 3.57 | 1B |
| Dustin Pedroia | 442 | 60 | 43 | 0.280 | 0.337 | 0.51 | 2B |
| Mike Aviles | 440 | 48 | 53 | 0.255 | 0.284 | 0.34 | SS |
| David Ortiz | 379 | 68 | 58 | 0.316 | 0.414 | 4.39 | DH |
| Cody Ross | 349 | 53 | 61 | 0.277 | 0.344 | 3.83 | RF-LF-DH |
| Jarrod Saltalamacchia | 328 | 43 | 47 | 0.228 | 0.284 | 1.80 | CR-DH |
| Will Middlebrooks | 286 | 34 | 54 | 0.288 | 0.325 | 2.57 | 3B |
| Daniel Nava | 242 | 32 | 27 | 0.251 | 0.372 | 0.55 | LF |
| Ryan Sweeney | 219 | 22 | 16 | 0.260 | 0.301 | -1.12 | RF-CF |
| Kevin Youkilis | 165 | 25 | 14 | 0.233 | 0.315 | 0.25 | 3B-1B |
| Jacoby Ellsbury | 160 | 23 | 10 | 0.264 | 0.312 | -0.27 | CF |
| Kelly Shoppach | 158 | 16 | 17 | 0.250 | 0.323 | -0.22 | CR |
| Nick Punto | 132 | 10 | 9 | 0.198 | 0.295 | -1.08 | 2B |
| Marlon Byrd | 106 | 9 | 7 | 0.270 | 0.283 | -0.79 | CF |
| Carl Crawford | 103 | 20 | 17 | 0.286 | 0.311 | 1.48 | LF |
| Darnell McDonald | 99 | 13 | 9 | 0.214 | 0.303 | 0.00 | X |
| Pedro Ciriaco | 96 | 10 | 11 | 0.333 | 0.333 | -0.03 | 3B-2B-SS-DH |
| Ryan Kalish | 85 | 11 | 5 | 0.203 | 0.247 | -0.30 | CF |
| Scott Podsednik | 76 | 9 | 8 | 0.368 | 0.382 | 0.01 | LF-CF |
| Mauro Gomez | 31 | 3 | 3 | 0.300 | 0.323 | -0.09 | 1B |
| Ryan Lavarnway | 26 | 0 | 0 | 0.125 | 0.192 | -0.61 | CR-DH |
| Brent Lillibridge | 16 | 0 | 0 | 0.125 | 0.125 | -0.37 | SS-3B |
| Jason Repko | 11 | 0 | 0 | 0.091 | 0.091 | -0.26 | X |
| Danny Valencia | 9 | 0 | 1 | 0.125 | 0.111 | -0.10 | 3B |
| Lars Anderson | 8 | 1 | 0 | 0.125 | 0.125 | -0.08 | X |
| Che-Hsuan Lin | 5 | 1 | 0 | 0.200 | 0.200 | -0.01 | X |
| Nate Spears | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 147.0 | 5.14 | 24 | 0 | X | -3.84 |
| Clay Buchholz | 131.7 | 4.24 | 20 | 0 | X | -0.66 |
| Felix Doubront | 122.7 | 4.70 | 22 | 0 | X | -1.92 |
| Josh Beckett | 121.3 | 5.19 | 20 | 0 | X | -3.31 |
| Franklin Morales | 68.3 | 3.16 | 7 | 28 | X | 1.38 |
| Alfredo Aceves | 58.7 | 4.14 | 0 | 54 | X | -0.16 |
| Daniel Bard | 55.0 | 5.24 | 10 | 1 | X | -1.56 |
| Aaron Cook | 51.7 | 4.70 | 9 | 0 | X | -0.82 |
| Scott Atchison | 46.0 | 1.96 | 0 | 37 | X | 2.22 |
| Matt Albers | 39.3 | 2.29 | 0 | 40 | X | 1.59 |
| Vicente Padilla | 39.0 | 4.62 | 0 | 41 | X | -0.54 |
| Mark Melancon | 30.3 | 7.12 | 0 | 28 | X | -2.19 |
| Andrew Miller | 29.7 | 3.03 | 0 | 38 | X | 0.69 |
| Clayton Mortensen | 27.3 | 1.65 | 0 | 13 | X | 1.52 |
| Daisuke Matsuzaka | 23.0 | 6.65 | 5 | 0 | X | -1.41 |
| Junichi Tazawa | 21.7 | 1.66 | 0 | 16 | X | 1.19 |
| Rich Hill | 13.7 | 2.63 | 0 | 17 | X | 0.44 |
| Justin Germano | 5.7 | 0.00 | 0 | 1 | X | 0.53 |
| Craig Breslow | 5.3 | 3.38 | 0 | 7 | X | 0.08 |
| Justin Thomas | 4.7 | 7.71 | 0 | 7 | X | -0.40 |
| Michael Bowden | 3.0 | 3.00 | 0 | 2 | X | 0.07 |
| Darnell McDonald | 1.0 | 27.00 | 0 | 1 | X | -0.54 |
| Andrew Bailey | 0.3 | 0.00 | 0 | 1 | X | 0.03 |
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