| Tm | Name | W | L | Start | End | |
|---|---|---|---|---|---|---|
| BAL | Paul Richards | 89 | 65 | Beg | End | |
| BOS | Billy Jurges | 15 | 27 | Beg | 19600607 | |
| BOS | Del Baker | 2 | 5 | 19600608 | 19600612 | |
| BOS | Pinky Higgins | 48 | 57 | 19600614 | End | |
| CHA | Al Lopez | 87 | 67 | Beg | End | |
| CHN | Charlie Grimm | 6 | 11 | Beg | 19600504 | |
| CHN | Lou Boudreau | 54 | 83 | 19600505 | End | |
| CIN | Fred Hutchinson | 67 | 87 | Beg | End | |
| CLE | Joe Gordon | 49 | 46 | Beg | 19600802 | |
| CLE | Jo-Jo White | 1 | 0 | 19600803 | 19600803 | |
| CLE | Jimmy Dykes | 26 | 32 | 19600805 | End | |
| DET | Jimmy Dykes | 44 | 52 | Beg | 19600802 | |
| DET | Billy Hitchcock | 1 | 0 | 19600803 | 19600803 | |
| DET | Joe Gordon | 26 | 31 | 19600805 | End | |
| KCA | Bob Elliott | 58 | 96 | Beg | End | |
| LAN | Walter Alston | 82 | 72 | Beg | End | |
| MIL | Chuck Dressen | 88 | 66 | Beg | End | |
| NYA | Casey Stengel | 16 | 15 | Beg | 19600527 | |
| NYA | Ralph Houk | 6 | 6 | 19600528 | 19600606 | |
| NYA | Casey Stengel | 75 | 36 | 19600607 | End | |
| PHI | Eddie Sawyer | 0 | 1 | Beg | 19600412 | |
| PHI | Andy Cohen | 1 | 0 | 19600414 | 19600414 | |
| PHI | Gene Mauch | 58 | 94 | 19600416 | End | |
| PIT | Danny Murtaugh | 95 | 59 | Beg | End | |
| SFN | Bill Rigney | 33 | 25 | Beg | 19600617 | |
| SFN | Tom Sheehan | 46 | 50 | 19600618 | End | |
| SLN | Solly Hemus | 86 | 68 | Beg | End | |
| TEX | Cookie Lavagetto | 73 | 81 | Beg | End |
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