| Starter | Tm | Tier | Game |
|---|---|---|---|
| Babe Adams | PIT | -2 | 191007280_PIT_CIN |
| George Mullin | DET | -1.68 | 191007280_CHA_DET |
| Tom Hughes | NYA | -1.58 | 191007271_NYA_BOS |
| Lew Moren | PHI | -1.33 | 191007260_PHI_PIT |
| Elmer Koestner | CLE | -1.19 | 191007262_CLE_OAK |
Based on accumulated WAA for this season up to 1910-07-28.
| Rank | WAA | Name | IP | Tm |
|---|---|---|---|---|
| +001+ | 6.63 | Walter Johnson | 226 | MIN |
| +002+ | 6.36 | Ed Walsh | 237.7 | CHA |
| +005+ | 5.52 | Russ Ford | 176.7 | NYA |
| +006+ | 5.48 | Chief Bender | 168 | OAK |
| +007+ | 4.9 | Cy Barger | 173.7 | LAN |
| +009+ | 4.73 | Orval Overall | 101 | CHN |
| +010+ | 4.66 | George McQuillan | 149.3 | PHI |
| +011+ | 4.52 | Jack Coombs | 179.3 | OAK |
| +013+ | 4.13 | King Cole | 133 | CHN |
| +014+ | 4.11 | Ray Collins | 136 | BOS |
| +015+ | 4.09 | Christy Mathewson | 187.3 | SFN |
| +016+ | 3.75 | Cy Morgan | 190.3 | OAK |
| +019+ | 3.34 | Nap Rucker | 182.3 | LAN |
| +021+ | 3.11 | Kirby White | 103.3 | TOT |
| +022+ | 2.92 | Doc White | 122 | CHA |
| +025+ | 2.74 | Mordecai Brown | 168 | CHN |
| +038+ | 2.08 | Jack Pfiester | 70.3 | CHN |
| +044+ | 1.82 | Eddie Plank | 159.3 | OAK |
| +045+ | 1.8 | Bill Donovan | 87.7 | DET |
| +046+ | 1.77 | Ed Summers | 111.3 | DET |
| +047+ | 1.72 | Frank Smith | 127.7 | CHA |
| +052+ | 1.48 | Charley Hall | 124.3 | BOS |
| +060+ | 1.37 | Hooks Wiltse | 119.7 | SFN |
| XXXXX | 1.13 | Deacon Phillippe | 66 | PIT |
| XXXXX | 1.12 | Addie Joss | 107.3 | CLE |
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