| Starter | Tm | Tier | Game |
|---|---|---|---|
| Shovel Hodge | CHA | -7.87 | 192108100_CHA_NYA |
| Ray Caldwell | CLE | -3.2 | 192108090_CLE_OAK |
| Dixie Davis | BAL | -2.37 | 192108090_BAL_MIN |
| Carl Holling | DET | -1.11 | 192108092_DET_BOS |
| Speed Martin | CHN | -0.89 | 192108080_SFN_CHN |
Based on accumulated WAA for this season up to 1921-08-10.
| Rank | WAA | Name | IP | Tm |
|---|---|---|---|---|
| +002+ | 11.18 | Red Faber | 256.3 | CHA |
| +003+ | 9.47 | Eppa Rixey | 211 | CIN |
| +009+ | 6.5 | George Mogridge | 210.7 | MIN |
| +011+ | 5.75 | Carl Mays | 230 | NYA |
| +013+ | 5.52 | Jesse Barnes | 178.3 | SFN |
| +015+ | 4.96 | Burleigh Grimes | 192 | LAN |
| +016+ | 4.75 | Bill Doak | 143.7 | SLN |
| +021+ | 4.1 | Babe Adams | 127.3 | PIT |
| +020+ | 4.1 | Wilbur Cooper | 226 | PIT |
| +022+ | 4.1 | Whitey Glazner | 164 | PIT |
| +023+ | 4.05 | Sad Sam Jones | 207 | BOS |
| +026+ | 3.54 | Stan Coveleski | 231.7 | CLE |
| +027+ | 3.48 | Waite Hoyt | 190.3 | NYA |
| +029+ | 3.36 | Bullet Joe Bush | 164.7 | BOS |
| +030+ | 3.24 | Pete Alexander | 166 | CHN |
| +033+ | 3.16 | Hugh McQuillan | 186.7 | ATL |
| +034+ | 2.77 | Joe Oeschger | 205 | ATL |
| +039+ | 2.58 | Dolf Luque | 218 | CIN |
| +048+ | 2.16 | Dana Fillingim | 158 | ATL |
| +049+ | 2.14 | Rube Marquard | 182.7 | CIN |
| +051+ | 2.1 | Bill Pertica | 149 | SLN |
| +060+ | 1.78 | Guy Morton | 61.3 | CLE |
| +064+ | 1.63 | Art Nehf | 168.3 | SFN |
| +075+ | 1.29 | Bob Shawkey | 158.3 | NYA |
| XXXXX | 1.24 | Dutch Leonard | 171.3 | DET |
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