| Starter | Tm | Tier | Game |
|---|---|---|---|
| Red Faber | CHA | 10.31 | 192109211_CHA_MIN |
| Eppa Rixey | CIN | 6.94 | 192109190_ATL_CIN |
| Carl Mays | NYA | 5.77 | 192109190_DET_NYA |
| Sad Sam Jones | BOS | 3.3 | 192109210_CLE_BOS |
| Jesse Barnes | SFN | 3.1 | 192109200_SFN_CHN |
| Starter | Tm | Tier | Game |
|---|---|---|---|
| Dickey Kerr | CHA | -2.52 | 192109200_CHA_MIN |
| Ray Caldwell | CLE | -2.36 | 192109210_CLE_BOS |
| Harvey Freeman | OAK | -1.66 | 192109190_BAL_OAK |
| Tom Zachary | MIN | -1 | 192109200_CHA_MIN |
| Bill Hubbell | PHI | -0.98 | 192109190_PHI_SLN |
Based on accumulated WAA for this season up to 1921-09-21.
| Rank | WAA | Name | IP | Tm |
|---|---|---|---|---|
| +002+ | 11.26 | Red Faber | 312.7 | CHA |
| +009+ | 8.36 | Eppa Rixey | 284.7 | CIN |
| +010+ | 8.22 | Burleigh Grimes | 277.3 | LAN |
| +011+ | 7.82 | Carl Mays | 316.7 | NYA |
| +015+ | 6.55 | Bill Doak | 193 | SLN |
| +017+ | 6.14 | George Mogridge | 270.7 | MIN |
| +018+ | 5.92 | Sad Sam Jones | 288.7 | BOS |
| +019+ | 5.84 | Waite Hoyt | 262.7 | NYA |
| +020+ | 5.83 | Jesse Barnes | 254 | SFN |
| +023+ | 5.19 | Stan Coveleski | 296 | CLE |
| +027+ | 4.55 | Wilbur Cooper | 300 | PIT |
| +028+ | 4.54 | Babe Adams | 153 | PIT |
| +029+ | 4.52 | Dolf Luque | 295 | CIN |
| +035+ | 3.99 | Clarence Mitchell | 172 | LAN |
| +037+ | 3.95 | Bill Pertica | 201 | SLN |
| +038+ | 3.83 | Bullet Joe Bush | 229.3 | BOS |
| +040+ | 3.72 | Rube Marquard | 255.7 | CIN |
| +042+ | 3.61 | Pete Alexander | 234.3 | CHN |
| +044+ | 3.49 | Johnny Morrison | 130 | PIT |
| +045+ | 3.4 | Dana Fillingim | 227.3 | ATL |
| +046+ | 3.21 | Fred Toney | 246.3 | SFN |
| +047+ | 3.13 | Joe Oeschger | 287.3 | ATL |
| +048+ | 3.08 | Jesse Haines | 227.3 | SLN |
| +049+ | 2.85 | Bill Sherdel | 136.3 | SLN |
| +051+ | 2.78 | Benn Karr | 97.3 | BOS |
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