| Starter | Tm | Tier | Game |
|---|---|---|---|
| Sam Jones | SFN | 4.43 | 195909070_SLN_SFN |
| Don Newcombe | CIN | 2.21 | 195909070_PHI_CIN |
| Frank Lary | DET | 2.08 | 195909060_OAK_DET |
| Vern Law | PIT | 1.93 | 195909060_PIT_PHI |
| Jerry Walker | BAL | 1.85 | 195909060_BAL_NYA |
| Starter | Tm | Tier | Game |
|---|---|---|---|
| Ray Narleski | DET | -2.52 | 195909072_DET_CLE |
| Robin Roberts | PHI | -2.36 | 195909060_PIT_PHI |
| Bennie Daniels | PIT | -1.9 | 195909072_PIT_ATL |
| Bill Fischer | MIN | -1.21 | 195909072_MIN_BAL |
| Ray Herbert | OAK | -1 | 195909060_OAK_DET |
Based on accumulated WAA for this season up to 1959-09-08.
| Rank | WAA | Name | IP | Tm |
|---|---|---|---|---|
| +004+ | 7.15 | Hoyt Wilhelm | 200.3 | BAL |
| +007+ | 6.57 | Warren Spahn | 256.3 | ATL |
| +008+ | 6.27 | Johnny Antonelli | 260 | SFN |
| +010+ | 5.95 | Sam Jones | 240.3 | SFN |
| +016+ | 5.21 | Camilo Pascual | 203.3 | MIN |
| +021+ | 4.33 | Larry Jackson | 234 | SLN |
| +026+ | 4.07 | Harvey Haddix | 201.7 | PIT |
| +027+ | 4.07 | Vern Law | 239 | PIT |
| +028+ | 3.98 | Bob Buhl | 170.3 | ATL |
| +030+ | 3.91 | Art Ditmar | 181 | NYA |
| +035+ | 3.59 | Don Newcombe | 202.7 | CIN |
| +037+ | 3.57 | Stu Miller | 156.7 | SFN |
| +039+ | 3.52 | Bob Shaw | 194.7 | CHA |
| +041+ | 3.5 | Bud Daley | 195.3 | OAK |
| +043+ | 3.5 | Bob Rush | 91.3 | ATL |
| +042+ | 3.5 | Roger Craig | 113 | LAN |
| +051+ | 3.32 | Jack Sanford | 193 | SFN |
| +052+ | 3.3 | Jerry Walker | 153 | BAL |
| +057+ | 3.16 | Billy O'Dell | 174.7 | BAL |
| +056+ | 3.16 | Early Wynn | 228.7 | CHA |
| +060+ | 3.06 | Frank Lary | 221.7 | DET |
| +064+ | 2.79 | Jim Perry | 121 | CLE |
| +067+ | 2.68 | Jim Owens | 196.3 | PHI |
| +069+ | 2.65 | Whitey Ford | 176.3 | NYA |
| +072+ | 2.36 | Don Mossi | 196 | DET |
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