| Starter | Tm | Tier | Game |
|---|---|---|---|
| Jim Bunning | PHI | 10.63 | 196606151_PHI_CIN |
| Juan Marichal | SFN | 10.06 | 196606160_HOU_SFN |
| Bob Gibson | SLN | 5.56 | 196606150_PIT_SLN |
| Mel Stottlemyre | NYA | 5.26 | 196606170_DET_NYA |
| Sam McDowell | CLE | 4.91 | 196606160_CLE_NYA |
| Starter | Tm | Tier | Game |
|---|---|---|---|
| Diego Segui | TEX | -2.53 | 196606170_CLE_TEX |
| Denny Lemaster | ATL | -2.37 | 196606150_NYN_ATL |
| Fred Talbot | NYA | -1.89 | 196606160_CLE_NYA |
| Sammy Ellis | CIN | -1.84 | 196606160_PHI_CIN |
| Earl Wilson | DET | -1.73 | 196606170_DET_NYA |
Based on accumulated WAA for this season up to 1966-06-17.
| Rank | WAA | Name | IP | Tm |
|---|---|---|---|---|
| +001+ | 5.27 | Sandy Koufax | 117.3 | LAN |
| +002+ | 5.25 | Juan Marichal | 129 | SFN |
| +005+ | 4.53 | Bob Gibson | 127 | SLN |
| +007+ | 4.19 | Jim Bunning | 118.7 | PHI |
| +009+ | 3.49 | Mike Cuellar | 67.3 | HOU |
| +011+ | 3.38 | Tommy John | 96.3 | CHA |
| +013+ | 2.8 | Mel Stottlemyre | 114.3 | NYA |
| +014+ | 2.74 | Jim Maloney | 82.7 | CIN |
| +024+ | 2.38 | Phil Ortega | 93.3 | TEX |
| +023+ | 2.38 | Pete Richert | 114 | TEX |
| +025+ | 2.36 | Claude Osteen | 104.7 | LAN |
| +026+ | 2.24 | Al Jackson | 68.3 | SLN |
| +029+ | 2.16 | Dennis Ribant | 60.7 | NYN |
| +030+ | 2.1 | Dick Ellsworth | 97.7 | CHN |
| +037+ | 1.91 | Don Nottebart | 39 | CIN |
| +042+ | 1.84 | Jim Kaat | 98.7 | MIN |
| +043+ | 1.83 | Joe Horlen | 76.7 | CHA |
| +047+ | 1.68 | Steve Barber | 81.7 | BAL |
| +051+ | 1.56 | Sam McDowell | 79 | CLE |
| +053+ | 1.55 | Jack Lamabe | 49 | CHA |
| +054+ | 1.53 | Gary Bell | 94.7 | CLE |
| +057+ | 1.51 | Chris Short | 119.3 | PHI |
| +058+ | 1.49 | Juan Pizarro | 40.3 | CHA |
| +063+ | 1.41 | Hank Aguirre | 48.3 | DET |
| +067+ | 1.37 | Whitey Ford | 40 | NYA |
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