| Starter | Tm | Tier | Game |
|---|---|---|---|
| Jorge Lopez | BAL | -7.18 | 202104160_BAL_TEX |
| Trevor Williams | CHN | -4.01 | 202104170_ATL_CHN |
| Jeff Hoffman | CIN | -2.92 | 202104160_CLE_CIN |
| Trevor Cahill | PIT | -2.24 | 202104170_PIT_MIL |
| Yusei Kikuchi | SEA | -2.05 | 202104160_HOU_SEA |
Based on accumulated WAA for this season up to 2021-04-17.
| Rank | WAA | Name | IP | Tm |
|---|---|---|---|---|
| +002+ | 1.86 | Tyler Glasnow | 24.7 | TBA |
| +005+ | 1.69 | Jacob deGrom | 20 | NYN |
| +006+ | 1.55 | Joe Musgrove | 19 | SDN |
| +007+ | 1.51 | Corbin Burnes | 18.3 | MIL |
| +008+ | 1.46 | Lance Lynn | 19.7 | CHA |
| +009+ | 1.34 | Carlos Rodon | 14 | CHA |
| +010+ | 1.31 | Michael Pineda | 18 | MIN |
| XXXXX | 1.22 | Dane Dunning | 15 | TEX |
| XXXXX | 1.19 | Anthony DeSclafani | 17 | SFN |
| XXXXX | 1.16 | Steven Matz | 18.3 | TOR |
| XXXXX | 1.11 | Joe Ross | 11 | WAS |
| XXXXX | 1.09 | Gerrit Cole | 18.3 | NYA |
| XXXXX | 1.06 | Johnny Cueto | 20 | SFN |
| XXXXX | 1.04 | Wade Miley | 11 | CIN |
| XXXXX | 1.04 | Matt Boyd | 19.3 | DET |
| XXXXX | 1.01 | Hyun Jin Ryu | 19 | TOR |
| XXXXX | 1.01 | Freddy Peralta | 13 | MIL |
| XXXXX | 1.01 | Clayton Kershaw | 24.7 | LAN |
| XXXXX | 1 | Shane Bieber | 21.3 | CLE |
| XXXXX | 0.98 | Taylor Widener | 17 | ARI |
| XXXXX | 0.97 | Danny Duffy | 12 | KCA |
| XXXXX | 0.96 | Marcus Stroman | 12.3 | NYN |
| XXXXX | 0.94 | Aaron Civale | 20.7 | CLE |
| XXXXX | 0.87 | JT Brubaker | 15.3 | PIT |
| XXXXX | 0.87 | Max Scherzer | 19 | WAS |
_