| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 364 | 50 | 35 | 0.294 | 0.335 | 0.25 | 2B |
| Manny Ramirez | 318 | 47 | 51 | 0.287 | 0.374 | 2.71 | LF |
| Kevin Youkilis | 307 | 47 | 47 | 0.312 | 0.381 | 2.55 | 1B-3B |
| Jacoby Ellsbury | 293 | 50 | 23 | 0.273 | 0.348 | 0.68 | CF-LF-RF |
| J.D. Drew | 278 | 55 | 48 | 0.309 | 0.417 | 4.19 | RF |
| Mike Lowell | 263 | 35 | 43 | 0.285 | 0.350 | 1.92 | 3B |
| Julio Lugo | 263 | 22 | 18 | 0.274 | 0.361 | -2.07 | SS |
| David Ortiz | 246 | 37 | 43 | 0.252 | 0.354 | 2.54 | DH |
| Jason Varitek | 240 | 17 | 25 | 0.233 | 0.312 | -1.31 | CR |
| Coco Crisp | 214 | 24 | 21 | 0.270 | 0.308 | -0.38 | CF |
| Sean Casey | 114 | 7 | 8 | 0.362 | 0.412 | -1.14 | 1B-DH |
| Kevin Cash | 89 | 5 | 9 | 0.241 | 0.315 | -0.65 | CR |
| Brandon Moss | 59 | 5 | 7 | 0.226 | 0.288 | -0.15 | LF-RF |
| Alex Cora | 58 | 3 | 4 | 0.275 | 0.362 | -0.65 | SS |
| Jed Lowrie | 48 | 6 | 7 | 0.310 | 0.333 | 0.22 | SS-3B |
| Joe Thurston | 9 | 0 | 0 | 0.000 | 0.111 | -0.21 | X |
| Jeff Bailey | 6 | 1 | 0 | 0.000 | 0.500 | -0.04 | 1B |
| Chris Carter | 3 | 1 | 0 | 0.667 | 0.667 | 0.03 | X |
| Jonathan Van Every | 3 | 0 | 0 | 0.333 | 0.333 | -0.07 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 103.7 | 3.13 | 17 | 0 | X | 2.56 |
| Tim Wakefield | 102.0 | 3.88 | 16 | 0 | X | 0.71 |
| Josh Beckett | 94.0 | 3.73 | 14 | 0 | X | 0.98 |
| Daisuke Matsuzaka | 70.0 | 3.21 | 13 | 0 | X | 1.58 |
| Clay Buchholz | 42.3 | 5.53 | 8 | 0 | X | -1.33 |
| Justin Masterson | 42.0 | 3.43 | 7 | 0 | X | 0.74 |
| Jonathan Papelbon | 36.0 | 2.00 | 0 | 36 | X | 1.83 |
| David Aardsma | 35.7 | 2.52 | 0 | 32 | X | 1.38 |
| Hideki Okajima | 33.7 | 3.21 | 0 | 33 | X | 0.77 |
| Bartolo Colon | 33.0 | 4.09 | 6 | 0 | X | 0.07 |
| Manny Delcarmen | 33.0 | 3.27 | 0 | 35 | X | 0.70 |
| Javier Lopez | 29.3 | 2.45 | 0 | 36 | X | 1.18 |
| Craig Hansen | 23.0 | 4.70 | 0 | 22 | X | -0.28 |
| Mike Timlin | 21.7 | 7.06 | 0 | 24 | X | -1.46 |
| Julian Tavarez | 12.7 | 6.39 | 0 | 9 | X | -0.65 |
| Chris Smith | 6.0 | 1.50 | 0 | 2 | X | 0.38 |
| Bryan Corey | 6.0 | 10.50 | 0 | 7 | X | -0.88 |
| David Pauley | 4.3 | 10.38 | 1 | 0 | X | -0.63 |
| Kyle Snyder | 1.7 | 21.60 | 0 | 2 | X | -0.68 |
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