| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Dustin Pedroia | 372 | 49 | 38 | 0.277 | 0.390 | 1.07 | 2B |
| Adrian Gonzalez | 371 | 59 | 75 | 0.353 | 0.407 | 6.02 | 1B |
| Jacoby Ellsbury | 363 | 57 | 40 | 0.298 | 0.358 | 2.31 | CF |
| Kevin Youkilis | 329 | 47 | 56 | 0.271 | 0.392 | 3.68 | 3B |
| David Ortiz | 316 | 50 | 49 | 0.302 | 0.383 | 3.54 | DH |
| Carl Crawford | 278 | 33 | 31 | 0.242 | 0.273 | 0.69 | LF |
| J.D. Drew | 229 | 20 | 18 | 0.234 | 0.332 | -0.98 | RF |
| Jed Lowrie | 216 | 27 | 25 | 0.270 | 0.319 | 0.78 | SS-3B |
| Jarrod Saltalamacchia | 187 | 21 | 21 | 0.251 | 0.326 | 0.35 | CR |
| Marco Scutaro | 160 | 17 | 14 | 0.267 | 0.325 | -0.21 | SS |
| Jason Varitek | 134 | 18 | 17 | 0.248 | 0.328 | 0.77 | CR |
| Mike Cameron | 105 | 9 | 9 | 0.149 | 0.210 | -0.39 | CF |
| Darnell McDonald | 61 | 5 | 6 | 0.125 | 0.197 | -0.17 | RF-LF-CF |
| Josh Reddick | 49 | 11 | 11 | 0.452 | 0.490 | 1.25 | RF-LF |
| Drew Sutton | 47 | 8 | 7 | 0.318 | 0.340 | 0.56 | X |
| Jose Iglesias | 4 | 0 | 0 | 0.000 | 0.000 | -0.09 | X |
| Yamaico Navarro | 1 | 1 | 1 | 1.000 | 1.000 | 0.19 | X |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jon Lester | 110.3 | 3.43 | 17 | 0 | X | 1.10 |
| Josh Beckett | 98.0 | 2.20 | 15 | 0 | X | 3.77 |
| Clay Buchholz | 82.7 | 3.48 | 14 | 0 | X | 0.71 |
| Tim Wakefield | 74.7 | 4.82 | 10 | 9 | X | -1.69 |
| John Lackey | 70.0 | 6.81 | 12 | 0 | X | -4.84 |
| Alfredo Aceves | 50.3 | 3.75 | 4 | 17 | X | 0.11 |
| Daniel Bard | 40.0 | 2.25 | 0 | 38 | X | 1.49 |
| Daisuke Matsuzaka | 37.3 | 5.30 | 7 | 1 | X | -1.26 |
| Jonathan Papelbon | 31.7 | 3.69 | 0 | 32 | X | 0.12 |
| Matt Albers | 30.3 | 2.97 | 0 | 26 | X | 0.63 |
| Dan Wheeler | 24.3 | 6.29 | 0 | 25 | X | -1.38 |
| Andrew Miller | 17.7 | 3.06 | 3 | 0 | X | 0.33 |
| Bobby Jenks | 14.7 | 6.75 | 0 | 17 | X | -0.99 |
| Scott Atchison | 13.3 | 4.72 | 0 | 7 | X | -0.27 |
| Hideki Okajima | 8.3 | 4.32 | 0 | 7 | X | -0.09 |
| Rich Hill | 8.0 | 0.00 | 0 | 9 | X | 0.72 |
| Michael Bowden | 7.0 | 1.29 | 0 | 6 | X | 0.42 |
| Franklin Morales | 4.7 | 3.86 | 0 | 5 | X | 0.00 |
| Tommy Hottovy | 4.0 | 6.75 | 0 | 8 | X | -0.27 |
| Felix Doubront | 2.7 | 6.75 | 0 | 3 | X | -0.18 |
| Dennys Reyes | 1.7 | 10.80 | 0 | 4 | X | -0.27 |
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