| Name | PA | R | RBI | BA | OBP | WAA | POS |
|---|---|---|---|---|---|---|---|
| Adam Dunn | 456 | 65 | 75 | 0.209 | 0.346 | 4.00 | DH-1B |
| Alejandro de Aza | 455 | 68 | 43 | 0.292 | 0.352 | 0.98 | CF-LF |
| Alex Rios | 427 | 67 | 68 | 0.317 | 0.349 | 4.15 | RF |
| Alexei Ramirez | 417 | 42 | 48 | 0.269 | 0.288 | -0.34 | SS |
| Paul Konerko | 411 | 54 | 52 | 0.315 | 0.389 | 1.48 | 1B-DH |
| Gordon Beckham | 405 | 45 | 38 | 0.226 | 0.274 | -0.79 | 2B |
| Dayan Viciedo | 363 | 40 | 51 | 0.249 | 0.289 | 1.04 | LF-DH |
| A.J. Pierzynski | 338 | 46 | 59 | 0.288 | 0.340 | 3.09 | CR |
| Kevin Youkilis | 146 | 24 | 25 | 0.256 | 0.377 | 1.72 | 3B-1B |
| Brent Morel | 125 | 14 | 5 | 0.174 | 0.216 | -0.94 | 3B |
| Orlando Hudson | 116 | 7 | 11 | 0.173 | 0.233 | -0.83 | 2B |
| Tyler Flowers | 99 | 11 | 3 | 0.198 | 0.263 | -0.85 | CR |
| Eduardo Escobar | 97 | 11 | 3 | 0.207 | 0.278 | -0.81 | X |
| Brent Lillibridge | 70 | 6 | 2 | 0.175 | 0.229 | -0.80 | SS-3B |
| Kosuke Fukudome | 51 | 2 | 4 | 0.171 | 0.294 | -0.57 | LF |
| Jordan Danks | 36 | 3 | 2 | 0.314 | 0.306 | -0.32 | LF-CF |
| Name | IP | ERA | Gs | Gr | SO | WAA |
|---|---|---|---|---|---|---|
| Jake Peavy | 148.0 | 3.04 | 21 | 0 | X | 3.32 |
| Chris Sale | 124.0 | 2.61 | 18 | 1 | X | 4.02 |
| Gavin Floyd | 122.0 | 4.43 | 20 | 0 | X | -1.21 |
| Philip Humber | 88.0 | 6.14 | 16 | 0 | X | -4.38 |
| Jose Quintana | 83.7 | 2.80 | 12 | 2 | X | 2.35 |
| John Danks | 53.7 | 5.70 | 9 | 0 | X | -2.13 |
| Matt Thornton | 47.0 | 3.64 | 0 | 52 | X | 0.40 |
| Nate Jones | 44.0 | 3.27 | 0 | 40 | X | 0.75 |
| Hector Santiago | 39.3 | 3.66 | 0 | 32 | X | 0.31 |
| Dylan Axelrod | 38.3 | 5.63 | 6 | 4 | X | -1.46 |
| Addison Reed | 38.0 | 3.79 | 0 | 42 | X | 0.19 |
| Zach Stewart | 30.0 | 6.00 | 1 | 17 | X | -1.40 |
| Jesse Crain | 28.0 | 2.25 | 0 | 30 | X | 1.14 |
| Will Ohman | 26.7 | 6.41 | 0 | 32 | X | -1.50 |
| Leyson Septimo | 8.3 | 4.32 | 0 | 9 | X | -0.06 |
| Eric Stults | 6.7 | 4.05 | 1 | 1 | X | -0.01 |
| Brian Omogrosso | 6.3 | 4.26 | 0 | 5 | X | -0.04 |
| Francisco Liriano | 6.0 | 3.00 | 1 | 0 | X | 0.14 |
| Brett Myers | 5.7 | 0.00 | 0 | 7 | X | 0.53 |
| Pedro Hernandez | 4.0 | 18.00 | 1 | 0 | X | -1.31 |
| Jhan Marinez | 1.7 | 0.00 | 0 | 1 | X | 0.16 |
| Donnie Veal | 1.7 | 0.00 | 0 | 2 | X | 0.16 |
| Brian Bruney | 1.0 | 0.00 | 0 | 1 | X | 0.09 |
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