| Tm | Name | W | L | Start | End | |
|---|---|---|---|---|---|---|
| BOS | Joe Cronin | 88 | 61 | Beg | End | |
| BOS | Casey Stengel | 77 | 75 | Beg | End | |
| CHA | Jimmy Dykes | 65 | 83 | Beg | End | |
| CHN | Charlie Grimm | 45 | 36 | Beg | 19380719 | |
| CHN | Gabby Hartnett | 44 | 27 | 19380721 | End | |
| CIN | Bill McKechnie | 82 | 68 | Beg | End | |
| CLE | Ossie Vitt | 86 | 66 | Beg | End | |
| DET | Mickey Cochrane | 47 | 51 | Beg | 19380806 | |
| DET | Del Baker | 37 | 19 | 19380807 | End | |
| LAN | Burleigh Grimes | 69 | 80 | Beg | End | |
| NYA | Joe McCarthy | 97 | 52 | Beg | 19380928 | |
| NYA | Art Fletcher | 1 | 0 | 19380929 | 19380929 | |
| NYA | Joe McCarthy | 1 | 1 | 19381001 | End | |
| OAK | Connie Mack | 53 | 99 | Beg | End | |
| PHI | Jimmie Wilson | 45 | 103 | Beg | 19380929 | |
| PHI | Hans Lobert | 0 | 2 | 19381002 | End | |
| PIT | Pie Traynor | 86 | 64 | Beg | End | |
| SFN | Bill Terry | 83 | 67 | Beg | End | |
| SLN | Frankie Frisch | 63 | 72 | Beg | 19380911 | |
| SLN | Gabby Street | 53 | 90 | Beg | 19380925 | |
| SLN | Mike Gonzalez | 8 | 8 | 19380914 | End | |
| SLN | Ski Melillo | 2 | 7 | 19380927 | End | |
| TEX | Bucky Harris | 75 | 76 | Beg | End |
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